Dimethyl Sulfoxide

DMSO is used as a topical analgesic, a vehicle for topical application of pharmaceuticals, as an anti-inflammatory and an antioxidant. FDA has approved the use of DMSO only for palliative treatment of interstitial cystitis. DMSO also use in the veterinary field as a liniment for horses.Use of DMSO in medicine dates from around 1963, when a University of Oregon Medical School team, headed by Stanley Jacob, discovered it could penetrate deeply through the skin and other membranes without damaging them and could carry other compounds deep into a biological system. Some people report an onion- or garlic-like taste after contact with the skin. This is likely due to catabolic processes which reduce DMSO to dimethyl sulfide. Because DMSO increases the rate of absorption of some compounds through organic tissues including skin, it can be used as a drug delivery system.

Brands
Adult Dose
Dose: Intravesical
Single Dose:
Frequency:
Route:
Instructions:
Neonatal
Paedriatic
Characteristics
Dimethyl Sulfoxide also known as Methyl sulfoxide, Methyl sulfoxide, Methyl sulfoxide. . It is of Synthetic origin. . The Molecular Weight of Dimethyl Sulfoxide is 78.13.
Contraindications
Dimethyl Sulfoxide is contraindicated in conditions like Hypersensitivity to any component of product.
Effects
The severe or irreversible adverse effects of Dimethyl Sulfoxide, which give rise to further complications include Hypersensitivity reactions, Erythema.The symptomatic adverse reactions produced by Dimethyl Sulfoxide are more or less tolerable and if they become severe, they can be treated symptomatically, these include Headache, Nausea, Vomiting, Diarrhea, Constipation, Erythema, Sedation, Itching, Burning.
Indications
Dimethyl Sulfoxide is primarily indicated in conditions like Palliative treatment of interstitial cystitis, and can also be given in adjunctive therapy as an alternative drug of choice in Arthritic pain, Herpes zoster.
Interactions
No data regarding the interactions of Dimethyl Sulfoxide was found.
Interfrence
Liver Function Test (LFT)
Risks
Drug should not be given to Paediatrics, and Pregnant Mothers.If prescribing authority justifies the benefits of the drug against the possible damages he/she should reevaluate them and consult the reference material and previous studies.
Storage
Store in a well closed container. Protect from Sunlight.
Warnings
The drug is asssociated with lens changes,therefore assessment of opthalmic function is required.
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