Pipercuronium

Pipercuronium is a competitive blocking agent. It produces its action by blocking ganglions at motor end plate.It has been used for endotracheal intubation and to provide muscle relaxation in general anesthesia for surgical procedures and to aid mechanical ventilation.

Brands
Adult Dose
Dose: 0.07 to 0.085 mg/kg
Single Dose: 0.078 (0.0775)
Frequency: As recommended.
Route:
Instructions:
Neonatal
Paedriatic
Characteristics
belongs to Ammonio steroid. It belongs to Competitive neuromuscular blocker pharmacological group on the basis of mechanism of action. The Molecular Weight of Pipercuronium is 762.70.
Contraindications
Pipercuronium is contraindicated in conditions like Hypersensitivity.
Effects
The severe or irreversible adverse effects of Pipercuronium, which give rise to further complications include Hypotension, Bradycardia.The signs and symptoms that are produced after the acute overdosage of Pipercuronium include prolonged action for surgery and anestheia, Cardiovascular disturbances.The symptomatic adverse reactions produced by Pipercuronium are more or less tolerable and if they become severe, they can be treated symptomatically, these include Skin rashes, Urticaria.
Indications
Pipercuronium is primarily indicated in conditions like Muscle relaxation in surgical anesthesia.
Interactions
No data regarding the interactions of Pipercuronium was found.
Interfrence
Increased in serum creatinin
Risks
Drug should not be given to Pregnant Mothers, and patients suffering from Kidney dysfunction.If prescribing authority justifies the benefits of the drug against the possible damages he/she should reevaluate them and consult the reference material and previous studies.
Storage
Warnings
This drug should not be used in following conditions: 1. Myaesthenia gravis 2. Severe obesity 3. Malignant hyperthermia
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