Guanadrel

Guanadrel belongs to a class of antihypertensive used in the treatment of hypertension.It works by controlling nerve impulses and inhibit norepinephrine as a result relaxes the blood vessels so that blood passes through them easily hence lowering the blood pressure.

Brands
Adult Dose
Dose: 5 to 25 mg
Single Dose: 15 (15)
Frequency: 12 hourly
Route: Oral
Instructions:
Neonatal
Paedriatic
Characteristics
. It is of Synthetic origin and belongs to guanidine. It belongs to Adrenergic Neurone Blockade pharmacological group on the basis of mechanism of action and also classified in Antihypertensive Agents pharmacological group.The Molecular Weight of Guanadrel is 213.28. It is weakly acidic drug.
Contraindications
Guanadrel is contraindicated in conditions like Asthma,Heart failure,Peptic ulcer,Stomatitis,Kidney disease.
Effects
The severe or irreversible adverse effects of Guanadrel, which give rise to further complications include Allergy, Anxiety, Weight gain, Dizziness, Chest pain, Heart failure, Blurred vision, Constipation.Guanadrel produces potentially life-threatening effects which include Heart failure. which are responsible for the discontinuation of Guanadrel therapy.The signs and symptoms that are produced after the acute overdosage of Guanadrel include Blurred vision, Fainting, Syncope, Orthoststic hypotension.The symptomatic adverse reactions produced by Guanadrel are more or less tolerable and if they become severe, they can be treated symptomatically, these include Dizziness, Drowsiness, Fatigue, Diarrhea, Fever, Rashes, Nasal congestion, Orthostatic hypotension, Loss of appetite, Swelling of feet, dizziness.
Indications
Guanadrel is primarily indicated in conditions like Hypertension.
Interactions
No data regarding the interactions of Guanadrel was found.
Interfrence
No well documented
Risks
Drug should not be given to patients suffering from Kidney dysfunction, Geriatrics, and Neonates.If prescribing authority justifies the benefits of the drug against the possible damages he/she should reevaluate them and consult the reference material and previous studies.
Storage
Drug Form Store at room temperature. Protect from Sunlight, Moisture and Heat.
Warnings
Use caution when driving, operating machinery, or performing other hazardous activities. Guanadrel may cause dizziness or drowsiness.Patient should avoid sudden position changes to prevent orthoststic hypotension.
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