Pargyline

Pargyline is a selective MAO-B inhibitor which functions by inhibiting the metabolism of catecholamines and tyramine within presynaptic nerve terminal.It is used to treat moderate to severe hypertension.

Brands
Adult Dose
Dose: 10 to 25 mg
Single Dose: 18 (17.5)
Frequency: 24 hourly
Route: oral
Instructions:
Neonatal
Paedriatic
Characteristics
It belongs to MAO Inhibitor pharmacological group on the basis of mechanism of action and also classified in Antiparkinson Agents and Hypertension pharmacological group.It is weakly acidic drug.
Contraindications
Pargyline is contraindicated in conditions like Liver damage,Kidney disease.
Effects
The severe or irreversible adverse effects of Pargyline, which give rise to further complications include Vertigo, Muscle twitching, Blurred vision.The symptomatic adverse reactions produced by Pargyline are more or less tolerable and if they become severe, they can be treated symptomatically, these include Dizziness, Headache, Vomiting, Fever, Insomnia, Sweating.
Indications
'Pargyline is primarily indicated in conditions like Hypertension, Parkinson''s disease.'
Interactions
No data regarding the interactions of Pargyline was found.
Interfrence
Risks
Drug should not be given to patients suffering from Kidney dysfunction, and patients suffering from Liver Malfunction.If prescribing authority justifies the benefits of the drug against the possible damages he/she should reevaluate them and consult the reference material and previous studies.
Storage
Warnings
Take dose at the same time.If unusual allergy reaction occur consult your doctor.Avoid alcohol or wine with pargyline.
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