Cetrorelix

Cetrorelix is luteinising hormone releasing hormone antagonist, which inhibits the release of gonadotrophins (luteinising hormone and follicle-stimulating hormone). It is used in the treatment of infertility by assisted reproductive techniques.


Adult Dose
Dose: 250 mcg
Single Dose: 250 (250)
Frequency: As recommended.
Route: SC
Instructions: In tothe lower abdominal wall ,starting on day 5 or 6 of ovarian stimulation with gonadotophins (or each evening starting on day 5 of ovarian stimulation); continue throughout administration of gonadotrophin including day of ovulation induction. or 3mg on day 7 of ovarian stimulation with gonadotrophins;if ovulation induction is not possible on day 5 after 3mg dose,additional 250mcg once.
Neonatal
Paedriatic
Characteristics
. It is of Synthetic origin. . The Molecular Weight of Cetrorelix is 1431.06.
Contraindications
Cetrorelix is contraindicated in conditions like Pregnancy,Prophylaxis of gout,Breast feeding,Listerial meningitis (adjunct).
Effects
The symptomatic adverse reactions produced by Cetrorelix are more or less tolerable and if they become severe, they can be treated symptomatically, these include Headache, Nausea, Hypersensitivity reactions, Injection site reactions.
Indications
Cetrorelix is primarily indicated in conditions like Acute diarrhoea, Adjunct in the treatment of female infertilty (under specialist supervision).
Interactions
No data regarding the interactions of Cetrorelix was found.
Interfrence
Risks
Drug should not be given to Pregnant Mothers, patients suffering from Kidney dysfunction, and Geriatrics.If prescribing authority justifies the benefits of the drug against the possible damages he/she should reevaluate them and consult the reference material and previous studies.
Storage
Inj Store at room temperature, Between 15°C-30°C. Protect from Sunlight, Moisture and Heat.
Warnings
Special care should be taken in women with signs and symptoms of active allergic conditions or known history of allergic predisposition. Treatment with Cetrorelix is not advised in women with severe allergic conditions. Drinking alcoholic beverages or smoking tobacco may decrease chances of becoming pregnant. Talk with your health care professional about not drinking alcohol and decreasing tobacco use during your fertility treatments.
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