Exemestane

A steroidal aromatase inhibitor, used in the treatment of advanced breast cancer in postmenopausal women in whom anti-estrogen therapy has failed.


Brands
Adult Dose
Dose: 25 mg
Single Dose: 25 (25)
Frequency: 24 hourly
Route: PO
Instructions:
Neonatal
Paedriatic
Characteristics
. It is of Synthetic origin. .
Contraindications
Exemestane is contraindicated in conditions like Pregnancy,Premenopausal breast cancer,Breast feeding.
Effects
The severe or irreversible adverse effects of Exemestane, which give rise to further complications include Tumors.Exemestane produces potentially life-threatening effects which include Breast cancer. which are responsible for the discontinuation of Exemestane therapy.The symptomatic adverse reactions produced by Exemestane are more or less tolerable and if they become severe, they can be treated symptomatically, these include Dizziness, Headache, Fatigue, Nausea, Vomiting, Alopecia, Anorexia, Constipation, Insomnia, Abdominal pain, Sweating, Peripheral edema, Rashes, Dyspepsia, Depression, Thrombocytopenia, Hot flushes, Leucopenia, Alopecia, dizziness, dyspepsia.
Indications
Exemestane is primarily indicated in conditions like Male hypersexuality, and can also be given in adjunctive therapy as an alternative drug of choice in Breast cancer.
Interactions
No data regarding the interactions of Exemestane was found.
Interfrence
Elevations of SGPT and SGOT Increased Alkaline Phosphatase LevelsIncreased in serum creatinin
Risks
Drug should not be given to patients suffering from Kidney dysfunction, and patients suffering from Liver Malfunction.If prescribing authority justifies the benefits of the drug against the possible damages he/she should reevaluate them and consult the reference material and previous studies.
Storage
Warnings
Exemestane Tablets should not be administered to premenopausal women. Exemestane should not be coadministered with estrogen-containing agents as these could interfere with its pharmacologic action.
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