Cisatracurium

Cisatracurium is a neuromuscular blocking agent, acts by competing with acetylcholine for receptors on the motor end-plate of the neuromuscular junction to produce blockade. Cisatracurium is a single isomer of atrcurium. Cisatracurium is more potent and has a slightly longer duration of action than atracurium. Cisatracurium is used as a muscle relaxant in general anaesthesia for surgical procedures.

Brands
Adult Dose
Dose: 3 mcg/kg of bodywt/min
Single Dose: 3 (3)
Frequency: As recommended.
Route: IV
Instructions: For surgery: This is initial dose and then decreased to 1 to 2 mcg (0.001 to 0.002 mg) per kg of body weight per minute.
Neonatal
Dose: 0.15 mg/kg
Single Dose: 0.15 (0.15)
Frequency: As recommended.
Route: over 5 to 10 sec during halothane or opoid anesthesia. (1st month to 23 month)
Instructions:
Paedriatic
Dose: 0.1 to 0.15 mg/kg
Single Dose: 0.12 (0.125)
Frequency: As recommended.
Route: for children 2-12years.
Instructions:
Characteristics
Cisatracurium besylate (Cisatrawrium) is the derivative of Cisatracurium. It is of Synthetic origin. . The Molecular Weight of Cisatracurium is 929.20. It is strongly acidic drug.
Contraindications
Cisatracurium is contraindicated in conditions like Hypersensitivity to any component of product.
Effects
The symptomatic adverse reactions produced by Cisatracurium are more or less tolerable and if they become severe, they can be treated symptomatically, these include Hypotension, Hypersensitivity reactions, Bronchospasm, Skin flushing.
Indications
Interactions
No data regarding the interactions of Cisatracurium was found.
Interfrence
Risks
Drug should not be given to Geriatrics.If prescribing authority justifies the benefits of the drug against the possible damages he/she should reevaluate them and consult the reference material and previous studies.
Storage
Drug Form
Warnings
Before receiving cisatracurium, tell your doctor if you have a muscle disorder such as myasthenia gravis, paralysis in any part of your body, an electrolyte imbalance, or a history of burn injury.
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