Remifentanil

Remifentanil is an opioid analgesic similar to fentanyl, used as an adjunct to general anaesthesia. Remifentanil is given as an induction agent since it has a rapid onset of action and an extremely short duration of action. Ramifentanil is metabolised very rapidly by blood and non-specific tissue esterases, making its pharmacokinetic and pharmacodynamic half-lives extremely short.

Brands

Adult Dose

Neonatal

Paedriatic

Characteristics

Contraindications

Remifentanil is contraindicated in conditions like Phaeochromocytoma,Raised intracranial pressure,Adjunct in cryptococcal meningitis.

Effects

The symptomatic adverse reactions produced by Remifentanil are more or less tolerable and if they become severe, they can be treated symptomatically, these include Drowsiness, Nausea, Vomiting, Constipation.

Indications

Remifentanil is primarily indicated in conditions like Obsessive-compulsive disorders, Severe shock due for example to cardiac arrest.

Interactions

No data regarding the interactions of Remifentanil was found.

Interfrence

Risks

If prescribing authority justifies the benefits of the drug against the possible damages he/she should reevaluate them and consult the reference material and previous studies.

Storage

Warnings

Skilled activities such as driving should be avoided because of drowsiness.

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