GLAX GLAX GLAX GLAX QUINTEC QUINTEC QUINTEC GETROLOX GETROLOX GATIQUIN GATIQUIN GATIQUIN FORTE RELE RELE OXIFECT OXIFECT LOXIGET EYE DROPS GATI GATI MEDIGET ZEQUIN ZEQUIN GENTALEK GATIWIN FLORQUIN GATICOBAXIN GATICOBAXIN FLOGET GATCIN GATCIN SANTOGAT SANTOGAT AQUIN AQUIN GETRAN GETRAN ZEXTRA ZEXTRA YAKTA TERIGET TERIGET LOXIGET FORTE LOXIGET EYE OINTMENT GATACIN GATACIN GATICIN GAXIN GATESIL GATESIL YAX YAX GATOX GEOX GEOX GETIF GATIDEX GATIDEX QUIXIN GRAYFLOX PANGIT PANGIT TEKWIN TEKWIN AGAT AGAT GATINEX GATINEX GATIJIN GACIN TREBAC TREBAC

Dose: 400 mg
Single Dose: 400 (400)
Frequency: 12 hourly
Route: PO
Instructions:

. It is of Synthetic origin and belongs to Fluoroquinolones. . The Molecular Weight of Gatifloxacin is 402.40.

Gatifloxacin is contraindicated in conditions like Diabetes mellitus,Hypersensitivity to the drug.

Gatifloxacin produces potentially life-threatening effects which include Coma, Convulsions, Diabetic ketoacidosis, Hyperosmolar non-ketotic hyperglycaemic coma. which are responsible for the discontinuation of Gatifloxacin therapy.The symptomatic adverse reactions produced by Gatifloxacin are more or less tolerable and if they become severe, they can be treated symptomatically, these include Dizziness, Diarrhea, Insomnia, Skin RashX, Nausea and vomiting, Abnormal LFT, Abdominal discomfort, QT prolongation, Hyperglycemia in diabetic patients, Hypoglycemia in patients also receiving oral hypoglycaemic agents, dizziness, Abnormal LFT.

Gatifloxacin is primarily indicated in conditions like Infections caused by Gram +ve organisms (particularly S.pneumoniae and to some extent staphylococci), Respiratory tract infections, Skin structure infections, Soft tissue infections, Uncomplicated skin, UTI.

Gatifloxacin is known to interact with other drugs, the details of drug interactions is as follows:DrugDetailsSeverityOnsetManagementVORICONAZOLEAdditive QTc prolongation may occur. Consider alternate therapy or monitor for QTc prolongation These interactions are sometimes beneficial and sometimes may pose threats to life. Always consult your physician for the change of dose regimen or an alternative drug of choice that may strictly be required.

Elevation in ALT or AST

Drug should not be given to Paediatrics, and Cardiac / Hypertensive Patients.If prescribing authority justifies the benefits of the drug against the possible damages he/she should reevaluate them and consult the reference material and previous studies.

Fluoroquinolones should be used with caution in patients with a history of epilepsy or conditions that predisposed to seizures, in G6PD deficiency, myasthenia gravis (risk of exacerbation), in pregnancy, during breast-feeding, and in children or adolescents (arthropathy has developed in weight bearing joints in young animals. Exposure to sunlight should be avoided (discontinue if photosensitivity occurs). The CSM has warned that quinolones may induce convulsions in patients with or without convulsions; taking NSAIDs at the same time may also induce them. USE IN CHILDREN: Quinolones cause athropathy in the weight-bearing joints of immature animals and are therefore generally not recommended in the children and growing adolescents. However, the significance of this effect in human is uncertain and in some specific circumstances short-term use of a quinolone in children may be justified. Gatifloxacin should not be givento diabetic patients.