Orlistat

Orlistat is a peptic and pancreatic lipase inhibitor that reduces the absorption of fat. Orlistat is used as an adjunct in the treatment of obesity, in those individuals who have a high intake of fats or in the presence of risk factors such as type II diabetes, hypertension and hypercholesterolemia.

Brands
ORLEAN ABNIL ORLOVIT ORLIS OBISTAT ORLIFIT FABECAL OSKER OSKER ORLISAT ORSLIM XENICAL SLIMTAB OSITA ZENCE ZENCE ORLIFT SLIMAX ZENEC TRIMZAK ORLICAL OBESTAT ORLIT ORLY APTEX
Adult Dose
Dose: 120 mg
Single Dose: 120 (120)
Frequency: 8 hourly
Route: PO
Instructions:
Neonatal
Paedriatic
Characteristics
Orlistat also known as Tetrahydrolipstatin. . It is of Synthetic origin. . The Molecular Weight of Orlistat is 495.70.
Contraindications
Orlistat is contraindicated in conditions like Cholestasis,Pregnancy,Breast feeding,Controlled hypotension in anaesthesia.
Effects
The symptomatic adverse reactions produced by Orlistat are more or less tolerable and if they become severe, they can be treated symptomatically, these include Flatulence, Headache, Fatigue, Anxiety, Abdominal pain, Hypersensitivity reactions, Menstrual irregularity, Fecal incontinence, Liquid oily stools, Rectal pain, Faecal urgency.
Indications
Orlistat is primarily indicated in conditions like Obesity.
Interactions
No data regarding the interactions of Orlistat was found.
Interfrence
Risks
Drug should not be given to Pregnant Mothers.If prescribing authority justifies the benefits of the drug against the possible damages he/she should reevaluate them and consult the reference material and previous studies.
Storage
Warnings
Orlistat should be used with caution in patients with diabetes mellitus. It may impair absorption of fat-soluble vitamins. MULTIVITAMINS: If a multivitamin suppliment is required, it should be taken atleast two hours after orlistat dose or at bedtime.
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