V-ZAC V-ZAC MODALERT MODALERT

Dose: 200 to 400 mg
Single Dose: 300 (300)
Frequency: 24 hourly
Route: PO
Instructions:

. The Molecular Weight of Modafinil is 273.30.

Modafinil is contraindicated in conditions like Pregnancy,Breast feeding,Myocardial infarction (non st-segment elevation),Hypertension of pregnancy,Hypertension with angina.

The symptomatic adverse reactions produced by Modafinil are more or less tolerable and if they become severe, they can be treated symptomatically, these include Headache, Nausea, Anorexia, Anxiety, Palpitation, Tachycardia, Insomnia, Nervousness, Abdominal pain, Dry mouth, Rashes, Pruritus, Hallucination, Depression, Psychosis, Tremor, Euphoria, Hypertension, GI disturbance, CNS stimulation, Excitation, Personality disorders, Gastric discomfort, Buccofacial dyskinesia, Dry mouth, nervousness, Nervousness.

Modafinil is primarily indicated in conditions like Narcolepsy, Sleep apnea syndrome.

Modafinil is known to interact with other drugs, the details of drug interactions is as follows:DrugDetailsSeverityOnsetManagementCyclosporin AConcurrent use may decrease the effectiveness of modafinil.Imipramine (HCl)Concomitant use may increase the toxicity of modafinil.Propranolol (HCl)Concomitant use may increase the toxicity of modafinil.TheophyllineConcomitant use may decrease the efficacy of modafinil.VORICONAZOLEVoriconazole may increase the serum concentration of modafinil by decreasing its metabolism. Monitor for changes in the therapeutic and adverse effects Warfarin (Na)Concomitant use may increase the toxicity of modafinil. These interactions are sometimes beneficial and sometimes may pose threats to life. Always consult your physician for the change of dose regimen or an alternative drug of choice that may strictly be required.

If prescribing authority justifies the benefits of the drug against the possible damages he/she should reevaluate them and consult the reference material and previous studies.

Oral tablets Store Between 20°C-25°C. Protect from Sunlight and Moisture.

Modafinil should be used with caution in patients with hepatic impairment (halve dose in severe liver disease); renal impairment (use half normal dose, if severe); monitor blood pressure and heart rate in hypertensive patients; possibility of dependence..Avoid alcohalic beverages.This medicine should be used only when clearly needed during pregnancy,discuses the risk and benefits with your doctor.Consult your dr before feeding. Not use for paediatrics in any indication.