Loprazolam

Loprazolam is an intermediate-acting benzodiazepine with actions and general properties similar to those of diazepam. Loprazolam is used as a hypnotic in the short-term management of insomnia.


Brands
Adult Dose
Dose: 1 mg
Single Dose: 1 (1)
Frequency: 24 hourly
Route: PO
Instructions: Dose can be increased to 2 mg if necessary.
Neonatal
Paedriatic
Characteristics
Loprazolam also known as Loprazolam Mesylate, Loprazolam Mesylate. . It is of Synthetic origin and belongs to Benzodiazapine. . The Molecular Weight of Loprazolam is 579.00.
Contraindications
Loprazolam is contraindicated in conditions like Myasthenia gravis,Respiratory depression,Acute pulmonary insufficiency,Sleep apnea syndrome.
Effects
The symptomatic adverse reactions produced by Loprazolam are more or less tolerable and if they become severe, they can be treated symptomatically, these include Vertigo, Drowsiness, Ataxia, Skin reactions, Light-headedness, Confusion, Dysuria, Muscle weakness, Tremor, Dysarthria, GI disturbance, Amnesia, Dependence, Salivation changes, Confusion, Ataxia.
Indications
Loprazolam is primarily indicated in conditions like Insomnia, Nausea, vertigo, labyrinthine disorders.
Interactions
No data regarding the interactions of Loprazolam was found.
Interfrence
Risks
If prescribing authority justifies the benefits of the drug against the possible damages he/she should reevaluate them and consult the reference material and previous studies.
Storage
Warnings
Loprazolam should be used with caution in patients with respiratory disease, muscle weakness, history of drug or alcohol abuse, marked personality disorder; avoid regular use during pregnancy (risk of neonatal withdrawl symptoms); use only if clear indication such as seizure control (high doses during late pregnancy or labour may cause neonatal hypothermia, hypotonia and respiratory depression); breast-feeding (present in milk, avoid if possible); reduce dose in elderly and debilitated, and in hepatic (avoid if severe) and renal impairment (start with small doses if severe); avoid prolong use (abrupt withdrawl thereafter); porphyria. It should not be used alone to treat depression (or anxiety associated with depression) or psychosis
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