Flunitrazepam

Flunitrazepam is a short acting benzodiazepine with actions, uses and adverse effects similar to that of diazepam. Flunitrazepam is used in short term management of insomnia, for induction of anaesthesia and as a premedication in surgical procedures.


Brands
Adult Dose
Neonatal
Paedriatic
Characteristics
.
Contraindications
Flunitrazepam is contraindicated in conditions like Myasthenia gravis,Respiratory depression,Acute pulmonary insufficiency,Sleep apnea syndrome.
Effects
The symptomatic adverse reactions produced by Flunitrazepam are more or less tolerable and if they become severe, they can be treated symptomatically, these include Vertigo, Drowsiness, Ataxia, Urinary retensionX, Confusion, Dysuria, Tremor, Light headedness, Dysarthria, GI disturbance, Amnesia, Dependence, Salivation changes, Incontinence.
Indications
Flunitrazepam is primarily indicated in conditions like Insomnia, Nausea, vertigo, labyrinthine disorders.
Interactions
No data regarding the interactions of Flunitrazepam was found.
Interfrence
Risks
If prescribing authority justifies the benefits of the drug against the possible damages he/she should reevaluate them and consult the reference material and previous studies.
Storage
Warnings
Flunitrazepam should be used with caution in patients with respiratory disease, muscle weakness, history of drug or alcohol abuse, marked personality disorder; avoid regular use during pregnancy (risk of neonatal withdrawl symptoms); use only if clear indication such as seizure control (high doses during late pregnancy or labour may cause neonatal hypothermia, hypotonia and respiratory depression); breast-feeding (present in milk, avoid if possible); reduce dose in elderly and debilitated, and in hepatic (avoid if severe) and renal impairment (start with small doses if severe); avoid prolong use (abrupt withdrawl thereafter); porphyria. It should not be used alone to treat depression (or anxiety associated with depression) or psychosis
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