Mepacrine (HCl)

Mepacrine (HCl) is an antiprotozoal agent. Mepacrine (HCl) is an acridine derivative, widely used during the second world war as an antimalarial agent, but now Mepacrine (HCl) is no longer used for this purpose, rather more safer and newer drugs are preferred. Mepacrine (HCl) is mainly used for the treatment of giardiasis. It has also been used locally for the treatment of certain cutaneous leishmaniasis.

Brands
Adult Dose
Dose: 100 mg
Single Dose: 100 (100)
Frequency: 8 hourly
Route: PO
Instructions: Should be given for 5 to 7 days.
Neonatal
Paedriatic
Dose: 2 mg/kg
Single Dose: 2 (2)
Frequency: As recommended.
Route: Maximum 300mg daily.
Instructions:
Characteristics
. The Molecular Weight of Mepacrine (HCl) is 508.91.
Contraindications
Mepacrine (HCl) is contraindicated in conditions like Psoriasis,Alcohol abuse,Hypersensitivity to the drug.
Effects
The symptomatic adverse reactions produced by Mepacrine (HCl) are more or less tolerable and if they become severe, they can be treated symptomatically, these include Dizziness, Headache, Nausea and vomiting, GI disturbance, CNS stimulation, Transient acute toxic psychosis, Yellow discolortaion of skin and urine, dizziness.
Indications
Mepacrine (HCl) is primarily indicated in conditions like Discoid lupus erythematosus, Giardiasis.
Interactions
No data regarding the interactions of Mepacrine (HCl) was found.
Interfrence
Risks
If prescribing authority justifies the benefits of the drug against the possible damages he/she should reevaluate them and consult the reference material and previous studies.
Storage
Warnings
Mepacrine (HCl) should be used with caution in patients with hepatic impairment; elderly, history of psychosis. Avoid in psoriasis.Porphyria
Back to List

Any information that appears on this website page is provided for the purpose of general information. This website has been compiled in good faith by HMIS.Online. However, no guarantee is made as to the completeness, validity or accuracy of the information it contains.