Caspofungin

Caspofungin is an antifungal agent, active against Aspergillus spp.and Candida spp. Caspofungin is given by intravenous infusion for invasive infection.


Brands
Adult Dose
Dose: 50 mg
Single Dose: 50 (50)
Frequency: 24 hourly
Route: IV
Instructions: An initial dose of 70 mg by i.v.-infusion is given followed by 50 mg i.v. daily. If no response is seen or if inducers of caspofungin clearance are coadministered the daily dose may be increased to 70 mg i.v. An infusion should take approximately 1 hour.
Neonatal
Paedriatic
Characteristics
. It is of Semi Synthetic origin. . The Molecular Weight of Caspofungin is 10931.31.
Contraindications
Caspofungin is contraindicated in conditions like Hypersensitivity to the drug,Breast feeding.
Effects
The symptomatic adverse reactions produced by Caspofungin are more or less tolerable and if they become severe, they can be treated symptomatically, these include Headache, Fever, Abdominal pain, Rashes, Pruritus, Flushing, Nausea and vomiting, Hypersensitivity reactions, Injection-site reactions.
Indications
Caspofungin is primarily indicated in conditions like Gastric acid reduction during anaesthesia, Peritonitis.
Interactions
No data regarding the interactions of Caspofungin was found.
Interfrence
Risks
Drug should not be given to patients suffering from Liver Malfunction.If prescribing authority justifies the benefits of the drug against the possible damages he/she should reevaluate them and consult the reference material and previous studies.
Storage
Powder,Sol Store Below 30°C. Do not Freeze. Protect from Moisture and Heat.
Warnings
Caspofungin should be used with caution in patients with hepatic impairment; pregnancy (avoid unless essential).
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