NEZOCIN NEZOCIN NEZOCIN NEZOCIN NEZOCIN NEZOCIN NEZOCIN ZOLREST ZOLREST LEZOL LEZOL RADIAL LINEXA LINZY LYZON LYZON LYZON IV LYZON IV LYZON IV LYZON IV HILID HILID WINY WINY ZYSPAN ZYSPAN ZYSPAN ZYSPAN NEZOLID NEZOLID NEZOLID NEZOLID NEZOLID NEZOLID NEZOLID Zyxoy NUZOL ECASIL ECASIL ECASIL ECASIL ECASIL NEZKIL NEZKIL NEZKIL NEZKIL LIZOTEK LIZOTEK LIZOTEK LIZOTEK LIZOTEK VOLINZA VOLINZA VOLINZA REKTO LENVOX LINZID LINZID LINZID VOXAM MICORCID Linlid Linlid Linez ALZOLID LINOSPAN LINOSPAN LINOSPAN LECKZOLID ZYXOCID ZYXOCID LIZOPES LIZOPES LEZOPES ZYWOCID Lizolid

Dose: 10 mg/kg
Single Dose: 10 (10)
Frequency: 8 hourly
Route: Orally
Instructions:

. It is of Synthetic origin and belongs to Oxazolidine. . The Molecular Weight of Linezolid is 337.50. Its pKa is 0.47.

Linezolid is contraindicated in conditions like Breast feeding.

The severe or irreversible adverse effects of Linezolid, which give rise to further complications include Convulsions, Stevens johnson syndrome, Stevens johnson syndrome, Leucopenia, Pancytopenia, Abnormal liver function, Anaemia, Lactic acidosis.The symptomatic adverse reactions produced by Linezolid are more or less tolerable and if they become severe, they can be treated symptomatically, these include Dizziness, Headache, Fatigue, Diarrhea, Fever, Constipation, Insomnia, Tinnitus, Dry mouth, Rashes, Urticaria, Pruritus, Hypotension, Nausea and vomiting, Tongue discoloration, Neuropathy, Dry mouth, dizziness.

Linezolid is primarily indicated in conditions like Pneumonia, Respiratory tract infections, Severe or recurrent duodenal and gastric ulcertion, Skin infections.

Linezolid is known to interact with other drugs, the details of drug interactions is as follows:DrugDetailsSeverityOnsetManagementAdrenalineDapoxetine HCl may lead to an incidence of serotonin associated effectsDapoxetine should not be used in combination with other SSRIs, MAOIs or other serotonergic medicinal/herbal products Dopamine (HCl)Phenylpropanolamine (HCl)Pseudoephedrine (HCl)Vortioxetineincrease toxicity of vortioxetinenever use combination These interactions are sometimes beneficial and sometimes may pose threats to life. Always consult your physician for the change of dose regimen or an alternative drug of choice that may strictly be required.

If prescribing authority justifies the benefits of the drug against the possible damages he/she should reevaluate them and consult the reference material and previous studies.

Store in a well closed container, .

Linezolid should be used with caution in patients with hepatic impairment; renal impairment; pregnancy (use only if potential benefit outweighs risk); monitor full blood count (including platelet count) weekly uless close observation and blood-pressure monitoring possible, avoid in uncontrolled hypertension, phaeocytochroma, carcinoid tumour, thyrotoxicosis, bipolar depression, schizophrenia, or acute confusional states. Monoamine Oxidase Inhibition: Linezolid is a reversible, non-selective monoamine oxidase inhibitor (MAOI). Patients should avoid consuming large amounts of tyramine-rich foods (such as mature cheese, yeast extracts, undistilled alcoholic beverages and fermented soya bean products). In addition, Linezolid should not be given with another MAOI or within two weeks of stopping another MAOI.Unless close observation and blood-pressure monitoringis possible, avoid in those receiving SSRIs, 5HT1 agonists (triptans), tricyclic antidepressants, sympathomimitics, dopaminergics, buspirone, pethidine and possibly other opiod analgesics.