Chorionic Gonadotrophin

Chorionic Gonadotrophin is a hormone produced in placenta. It stimulates the ovaries and the testes. Chorionic Gonadotrophin is used in males to stimulate testicular descent or testicular growth and development. In females, Chorionic Gonadotrophin is used in combination with other medication to induce ovulation.


Adult Dose
Dose: 5000 to 10000 IU
Single Dose: 7500 (7500)
Frequency: As recommended.
Route: IM
Instructions: According to patient`s response.
Neonatal
Dose:
Single Dose:
Frequency:
Route:
Instructions: Not recommended in this age group
Paedriatic
Dose: 50 to 100 IU/kg
Single Dose: 75 (75)
Frequency: As recommended.
Route: Intra Muscular
Instructions: Alternate days for several weeks, (for boys)
Characteristics
. It is of Natural origin and belongs to Glycoprotein. It belongs to LH-agonist pharmacological group on the basis of mechanism of action and also classified in Sex Hormones and Gonadotrophin pharmacological group.The Molecular Weight of Chorionic Gonadotrophin is 100000.00.
Contraindications
Chorionic Gonadotrophin is contraindicated in conditions like Precocious puberty,Ovarian hyperstimulation syndrome (OHS),Edema.
Effects
The severe or irreversible adverse effects of Chorionic Gonadotrophin, which give rise to further complications include Precocious puberty.Chorionic Gonadotrophin produces potentially life-threatening effects which include Ovarian hyperstimulation syndrome (OHSS). which are responsible for the discontinuation of Chorionic Gonadotrophin therapy.The symptomatic adverse reactions produced by Chorionic Gonadotrophin are more or less tolerable and if they become severe, they can be treated symptomatically, these include Tiredness, Headache, Restlessness, Depression, Edema, Gynecomastia, Mood changes, Reaction at injection site, Pain at injection site, Pain at injection site.
Indications
Chorionic Gonadotrophin is primarily indicated in conditions like Cryptorchidism (undescended testes), Hypogonadotrophic hypogonadism, Idiopathic male infertility, Induction of ovarian follicle maturation.
Interactions
No data regarding the interactions of Chorionic Gonadotrophin was found.
Interfrence
Interfere with the Pregnancy Test
Risks
Drug should not be given to Paediatrics, Pregnant Mothers, Geriatrics, and Neonates.If prescribing authority justifies the benefits of the drug against the possible damages he/she should reevaluate them and consult the reference material and previous studies.
Storage
Store Below 30°C.
Warnings
Chorionic gonadotrophin should not be used during pregnancy. It should be used with caution in patients with history of heart disease, kidney disease, asthma, migraine headaches, seizure disorder, cancer or any allergy.
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