Acamprosate Calcium

Acamprosate Calcium is an analog of GABA (Gamma amino-butyric acid), a neurotransmitter. It has chemical structure similar to GABA, acts as an agonist to GABA receptors, and reduces craving for alcohol. Acamprosate Calcium is used to prevent relapse in alcoholics who have been weaned off alcohol. Treatment should be started as soon as possible after alcohol withdrawl and maintained, even if the patient relapses, for the recommended period of 1 year.

Brands
Adult Dose
Dose: 333 mg thrice day
Single Dose: 330 (333)
Frequency: As recommended.
Route: PO
Instructions: This dose is for patients with renal impaired function.
Neonatal
Paedriatic
Characteristics
. It is of Combo1 origin. .
Contraindications
Acamprosate Calcium is contraindicated in conditions like Pregnancy,Renal impairment,Breast feeding.
Effects
The severe or irreversible adverse effects of Acamprosate Calcium, which give rise to further complications include Anxiety, Depression, Dizziness.The symptomatic adverse reactions produced by Acamprosate Calcium are more or less tolerable and if they become severe, they can be treated symptomatically, these include Diarrhea, Abdominal pain, Pruritus, Nausea and vomiting, Fluctuation in libido, Bullous skin reactions.
Indications
Acamprosate Calcium is primarily indicated in conditions like Alcohol dependence.
Interactions
No data regarding the interactions of Acamprosate Calcium was found.
Interfrence
Risks
Drug should not be given to Paediatrics, Pregnant Mothers, patients suffering from Kidney dysfunction, patients suffering from Liver Malfunction, and Neonates.If prescribing authority justifies the benefits of the drug against the possible damages he/she should reevaluate them and consult the reference material and previous studies.
Storage
Tablet Store at room temperature.
Warnings
Caution should be required in continued alcohol abuse (risk of treatment failure). Treatment should be started as soon as possible after alcohol withdrawal and maintained, even if the patient relapses, for the recommended period of 1 year. Continued alcohol abuse, however negates the therapeutic benefit of acamprosate.
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