Pramipexole

Pramipexole is directly acting dopamine-receptor (D-2) agonist, similar to bromocriptine. Pramipexole is used alone or as an adjunct in the treatment of parkinsonism. It also has some mood-elevating properties.

Brands

Adult Dose

Dose: 0.375 mg/day
Single Dose: 0.38 (0.375)
Frequency: As recommended.
Route: PO
Instructions: Should be given in 3 divided doses, increase gradually by 0.125 mg/dose every 5-7 days. Range: 1.5-4.5 mg/day

Neonatal

Paedriatic

Characteristics

Contraindications

Pramipexole is contraindicated in conditions like Breast feeding.

Effects

The symptomatic adverse reactions produced by Pramipexole are more or less tolerable and if they become severe, they can be treated symptomatically, these include Dizziness, Drowsiness, Constipation, Peripheral edema, Hallucination, Nausea and vomiting, Dyskinesia.

Indications

'Pramipexole is primarily indicated in conditions like Parkinson''s disease.'

Interactions

No data regarding the interactions of Pramipexole was found.

Interfrence

Risks

If prescribing authority justifies the benefits of the drug against the possible damages he/she should reevaluate them and consult the reference material and previous studies.

Storage

Warnings

Pramipexole should be used with caution in patients with renal impairment (May need dose reduction); psychotic disorders; opthamological testing recommended (risk of visual disorders); severe cardiovascular disease; pregnancy (use only if potential benefit outweighs risk); avoid abrupt withdrawl (risk of neuroleptic malignant syndrome).

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