Levetiracetam

Levetiracetam is an anti-epileptic drug which is used for the adjunctive treatment of partial seizures, with or without secondary generalisation.


Adult Dose
Dose: 1000 mg/day
Single Dose: 1000 (1000)
Frequency: As recommended.
Route: PO
Instructions: Additional dosing increments may be given (1000 mg/day additional every 2 weeks) to a maximum recommended daily dose of 3000 mg.
Neonatal
Paedriatic
Dose: 20 mg
Single Dose: 20 (20)
Frequency: As recommended.
Route: PO
Instructions: To maximum of 60 mg/kg daily.
Characteristics
. It is of Synthetic origin and belongs to Piracetan. . The Molecular Weight of Levetiracetam is 170.20.
Contraindications
Levetiracetam is contraindicated in conditions like Breast feeding.
Effects
The severe or irreversible adverse effects of Levetiracetam, which give rise to further complications include Thrombocytopenia, Neutropenia, Pancytopenia.Levetiracetam produces potentially life-threatening effects which include Hepatic impairment. which are responsible for the discontinuation of Levetiracetam therapy.The symptomatic adverse reactions produced by Levetiracetam are more or less tolerable and if they become severe, they can be treated symptomatically, these include Weakness, Dizziness, Vertigo, Headache, Drowsiness, Ataxia, Alopecia, Anorexia, Nervousness, Rashes, Depression, Somnolence, Tremor, Diplopia, Asthenia, Aggression, Alopecia, nervousness, Nervousness, dizziness, Ataxia, Weakness.
Indications
'Levetiracetam is primarily indicated in conditions like Anxiety, Epilepsy, Myoclonic seizures, and can also be given in adjunctive therapy as an alternative drug of choice in Alzheimer''s disease, Autism, Iron deficiency anaemia, Neuropathic pain, Tourette''s syndrome.'
Interactions
Levetiracetam is known to interact with other drugs, the details of drug interactions is as follows:DrugDetailsSeverityOnsetManagementLacosamide These interactions are sometimes beneficial and sometimes may pose threats to life. Always consult your physician for the change of dose regimen or an alternative drug of choice that may strictly be required.
Interfrence
Risks
Drug should not be given to Pregnant Mothers, patients suffering from Kidney dysfunction, and patients suffering from Liver Malfunction.If prescribing authority justifies the benefits of the drug against the possible damages he/she should reevaluate them and consult the reference material and previous studies.
Storage
Warnings
Levetiracetam should be used with caution in patients with hepatic impairment (Halve dose in severe hepatic impairment due to cocomitant renal impairment); renal impairment (May need dose reduction a/c to creatinine clearance); pregnancy (use only if potential benefits outweighs risk); avoid sudden withdrawl.
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