NARAN NARAN

Dose: 1 to 2.5 mg
Single Dose: 1.8 (1.75)
Frequency: As recommended.
Route: PO
Instructions: If the migraine comes back after being relieved, another dose may be taken four hours after the last dose. Do not take more than 5 mg in any twenty-four-hour period (one day).

. It is of Synthetic origin and belongs to Indole. . The Molecular Weight of Naratriptan is 371.90.

Naratriptan is contraindicated in conditions like Peripheral vascular disease,Ischaemic heart disease,Uncontrolled hypertension,Adjunct in treatment of opioid dependance,Chronic intractable hypoglycaemia.

The symptomatic adverse reactions produced by Naratriptan are more or less tolerable and if they become severe, they can be treated symptomatically, these include Dizziness, Fatigue, Dysuria, Flushing, Nausea and vomiting, Tingling, Heaviness, Tightness of any part of body, Bradycardia or tachycardia.

Naratriptan is primarily indicated in conditions like Migraine.

Naratriptan is known to interact with other drugs, the details of drug interactions is as follows:DrugDetailsSeverityOnsetManagementCitalopram (HBr)Concurrent use is not recommended, but dosages should be adjusted if concurrent use is required.Dihydroergotamine (Mesylate)Concurrent use have been reported to cause prolonged vasospastic reactions. Concurrent use is not recommended.Ergotamine (Tartrate)Concurrent use have been reported to cause prolonged vasospastic reactions. Concurrent use is not recommended.Fluoxetine (HCl)Concurrent use is not recommended, but dosages should be adjusted if concurrent use is required.Methysergide (Hydrogen Maleate)Concurrent use have been reported to cause prolonged vasospastic reactions. Concurrent use is not recommended.Nefazodone (HCl)Concurrent use is not recommended, but dosages should be adjusted if concurrent use is required.ParoxetineConcurrent use is not recommended, but dosages should be adjusted if concurrent use is required.Sertraline (HCl)Concurrent use is not recommended, but dosages should be adjusted if concurrent use is required.SumatriptanConcurrent use is not recommended.Vortioxetineincreases the level of vortioxetineuse alternative These interactions are sometimes beneficial and sometimes may pose threats to life. Always consult your physician for the change of dose regimen or an alternative drug of choice that may strictly be required.

Drug should not be given to patients suffering from Kidney dysfunction, and Geriatrics.If prescribing authority justifies the benefits of the drug against the possible damages he/she should reevaluate them and consult the reference material and previous studies.

5HT1 agonists (e.g Naratriptan) should be used with caution in conditions which predispose to coronary artery disease (pre-existing cardiac disease), pregnancy and breast-feeding. 5HT1 agonists are recommended as monotherapy and should not be taken concurrently with other acute migraine therapies. Little information is available on the use of these drugs in the elderly (over 65 year). Caution is also required in mild or moderate hepatic impairment; sensitivity to sulphonamides.