Levocetirizine

Levocetirizine Dihydrochloride is an isomer of cetrizine, a non-sedating antihistamine used for the treatment of allergic conditions, such as hay fever, urticaria.


Adult Dose
Dose: 5 mg
Single Dose: 5 (5)
Frequency: 24 hourly
Route: PO
Instructions:
Neonatal
Paedriatic
Dose: 2.5 mg
Single Dose: 2.5 (2.5)
Frequency: As recommended.
Route:
Instructions:
Characteristics
Levocetirizine [HCl], Levocetirizine [HCl], Levocetirizine [HCl] are the derivatives of Levocetirizine. It is of Synthetic origin. . The Molecular Weight of Levocetirizine is 388.60.
Contraindications
Levocetirizine is contraindicated in conditions like Porphyria,Adjunct in treatment of opioid dependance.
Effects
Levocetirizine produces potentially life-threatening effects which include Agranulocytosis, Thrombocytopenia, Pancytopenia, Paresthesia. which are responsible for the discontinuation of Levocetirizine therapy.The symptomatic adverse reactions produced by Levocetirizine are more or less tolerable and if they become severe, they can be treated symptomatically, these include Drowsiness, Nausea, Dyspnea, Confusion, Sleep disturbance, Depression, Hypersensitivity reactions, Bronchospasm, Blood dyscrasias, Convulsions, Angioedema, Liver dysfunction, Incidence of sedation, Antimucarinic effects, Confusion.
Indications
Levocetirizine is primarily indicated in conditions like Chronic urticaria, NSAID associated ulceration, Rhinitis, To prevent recurrence of neural tube defect.
Interactions
No data regarding the interactions of Levocetirizine was found.
Interfrence
Increases Serum Bilirubin
Risks
Drug should not be given to Pregnant Mothers.If prescribing authority justifies the benefits of the drug against the possible damages he/she should reevaluate them and consult the reference material and previous studies.
Storage
Warnings
Antihistamines (e.g Levocetirizine Dihydrochloride) should be used with caution in prostatic hypertrophy, urinary retention, epilepsy, glaucoma, pyloroduodenal obstruction, hepatic disease. Caution may also be required in pregnancy and breast-feeding. Children and the elderly are more susceptible to side-effects.
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