Acrivastine

Acrivastine is a non-sedating antihistamine structurally related to triprolidine. Acrivastine is used for symptomatic relief of allergy such as hay fever, urticaria. Incidence of antimuscarinic and sedating effects low.


Brands
Adult Dose
Dose: 8 to 60 mg/day
Single Dose: 34 (34)
Frequency: As recommended.
Route: PO
Instructions: This dose is for Allergic rhinitis and nasal congestion.
Neonatal
Paedriatic
Characteristics
Acrivastine also known as Proponic acid, Proponic acid. . It is of Synthetic origin and belongs to Alkylamine antihistamine. . The Molecular Weight of Acrivastine is 348.44.
Contraindications
Acrivastine is contraindicated in conditions like Renal impairment,Porphyria.
Effects
The severe or irreversible adverse effects of Acrivastine, which give rise to further complications include Increased blood pressure, Bleeding, Dizziness, Fast or uneven Heartbeat.Acrivastine produces potentially life-threatening effects which include Breathing Difficulty, Swelling of tongue or throat, Infection of Hives. which are responsible for the discontinuation of Acrivastine therapy.The signs and symptoms that are produced after the acute overdosage of Acrivastine include Seizures, Drowsiness, Dry mouth, Restlessness.The symptomatic adverse reactions produced by Acrivastine are more or less tolerable and if they become severe, they can be treated symptomatically, these include Headache, Drowsiness, Palpitation, Hypersensitivity reactions, Angioedema, Anticholinergic side effects, Anaphylaxis.
Indications
Acrivastine is primarily indicated in conditions like Decongestant, Hay fever, Rhinitis, Urticaria, and can also be given in adjunctive therapy as an alternative drug of choice in Uncomplicated gonorrhoea.
Interactions
No data regarding the interactions of Acrivastine was found.
Interfrence
Risks
Drug should not be given to Pregnant Mothers, patients suffering from Kidney dysfunction, patients suffering from Liver Malfunction, and Geriatrics.If prescribing authority justifies the benefits of the drug against the possible damages he/she should reevaluate them and consult the reference material and previous studies.
Storage
Capsules Store Between 15°C-25°C. Protect from Moisture and Heat.
Warnings
Antihistamines (e.g Acravastine) should be used with caution in prostatic hypertrophy, urinary retention, epilepsy, glaucoma, pyloroduodenal obstruction, hepatic disease. Caution may also be required in pregnancy and breast-feeding. Children and the elderly are more susceptible to side-effects. Donot drink alcohol while taking this medicine. Ensure patient understands about medicine, how to use it.
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