Dantron

Dantron is an anthraquinone stimulant laxative. Dantron is used in the treatment of constipation, but its used is now restricted only to elderly, or to terminally ill patients, because of the concern over rodent carcinogenicity.

Brands
Adult Dose
Dose: 8 mg
Single Dose: 8 (8)
Frequency: As recommended.
Route: PO
Instructions: For patients receiving emetogenic chemotherapy or radiotherapy: This dose should be administered 1-2 hours before treatment, followed by 8 mg orally twelve hourly.
Neonatal
Paedriatic
Dose: 25 to 12.5 mg
Single Dose: 19 (18.75)
Frequency: As recommended.
Route: P/O
Instructions: Age 12 or above.
Characteristics
Dantron also known as Danthron. . It is of Natural origin and belongs to Anthraquinones. . The Molecular Weight of Dantron is 240.21.
Contraindications
Dantron is contraindicated in conditions like Pregnancy.
Effects
The symptomatic adverse reactions produced by Dantron are more or less tolerable and if they become severe, they can be treated symptomatically, these include Abdominal cramps, Colored (red) urine.
Indications
Dantron is primarily indicated in conditions like Constipation.
Interactions
No data regarding the interactions of Dantron was found.
Interfrence
Risks
Drug should not be given to Paediatrics.If prescribing authority justifies the benefits of the drug against the possible damages he/she should reevaluate them and consult the reference material and previous studies.
Storage
Warnings
The indications for Dantron are limited by its potential carcinogenicity (based on rodent carcinogenic studies) and evidence of genototoxicity. It should not be used in infants wearing nappies (Diapers) As it may cause discoloration and sloughing of skin.
Back to List

Any information that appears on this website page is provided for the purpose of general information. This website has been compiled in good faith by HMIS.Online. However, no guarantee is made as to the completeness, validity or accuracy of the information it contains.