Esomeprazole

Esomeprazole is an ulcer-healing drug, that inhibits gastric acid by blocking the proton-pump (Hydrogen-Potassium atpase enzyme system) of the gastric perital cells. Esomeprazole is used for the short-term treatment of gastric and duodenal ulcers and in gastro-oesophageal reflux disease with severe symptoms. Esomeprazole is also used in combination with antibacterials for the eradication of Helicobacter pylori.


Brands
ESOMEPRAL ESOMEPRAL ECOROX ECOROX MELDERE MELDERE ESTRO ESTRO AXID NEO AXID NEO BENPROL BENPROL ESGERD ESGERD E ZOL E ZOL E CAP E CAP ESOPHAG ESOPHAG SOMEZOL SOMEZOL SOMEZOL ACIREG ACIREG ESPRA ESPRA EPRAZID EFROZOLE EFROZOLE PESSO ESOPASE ESOPASE ESSOCAM ESSOCAM NEXOM SOMICID SOMICID ESOPEP ESOPEP ESOPEP ESMAZOLE ESMAZOLE ESOCUE ESOCUE NEXUM NEXUM NEXUM AXESOM AXESOM ESORID ESORID ESKEM ARYSA ARYSA ZOLERIC ZOLERIC PARAZOLE PEP-EEZ INDAZOLE INDAZOLE ES-MYZOLE ESPRAZ ESOCAP ESOCAP ESANTE ESANTE ESOMAX ESOMAX EZTOMAC EZTOMAC REXIUM REXIUM PROTOHIB PROTOHIB ESMED MEDIRIUM MEDIRIUM ACILOC ACILOC ZOLSURE NESO NESO EXZIUM EXZIUM AVINZA ESVIN ESVIN ES-LOPROT ES-LOPROT ES-LOPROT ES-LOPROT SAPHIRE SAPHIRE REGULAX REGULAX RELIX RELIX OBPRA OBPRA ESONEN ESONEN ESSOM ESSOM FASTESO FASTESO ESOPRIME ESOPRIME EZOMOL EZOMOL ESMITEC ESMITEC EPI-40 EPI-20 SOGO GUTSY GUTSY ESOPULSE ESOROK ESOROK GERDPILL GERDPILL EUPAZOLE EUPAZOLE TRUTIL TRUTIL NOVOTEPH NOVOTEPH NOVOTEPH ESOCOOL ESOCOOL UL-SOME UL-SOME EZIUM EZIUM CONTOUR EZUMAC EZUMAC VIVID CAPSULE VIVID CAPSULE ESOZIL ESOZIL ESOMALT ESOMALT ESSO-20 ESSO-40 ESSO-40 SOMRIT SOMRIT SOMPRAZ SOMPRAZ ZUMIN ZUMIN T-XIUM T-XIUM OMEPLUS OMEPLUS ESOPROTO ESOPROTO ESOPROTO ZIMES ZIMES SOMEPRA SOMEPRA GOCID GOCID BIOPRAZOLE BIOPRAZOLE ESOPRAZOL ESOPRAZOL E-MEPRA E-MEPRA ESAPROL ESO MINE E-Z E-Z EZMA EZMA ESOGENT ESOGENT PEP-EASE PEP-EASE ESOFIL ESOFIL XESTRA XOCREL XOCREL ZOPRIL ZOPRIL S-OM S-OM OXILANT OXILANT QUPRA QUPRA JITS JITS ESO-ONE PLUS ESO-ONE EMPRAZOLE ESMA ESMA ESOFAG ESOFAG H2 EESOFAC NEXPRO NEXPRO NYLOZ NYLOZ ESOFAST ESOFAST GENZOLE GENZOLE OPA ES-CAY ES-CAY ESOMEGA ESOMEGA ESPROL ESPROL EZIPEP EZIPEP SOMPRA UNIZOLE ESOSCOT ESOSCOT ESOZEB F-ESO F-ESO EZO EZO E ZOLE E ZOLE ESCAR ESCAR PEPNOR PEPNOR EMPEL EMPEL NEXAPRAZOLE NEXAPRAZOLE ESOCARE ESOCARE ESOZOLE ESOZOLE PRABEST PRABEST ESOLIVE ESOLIVE EVERESO ESOPRA ESOPRA SOMELINZ SOMELINZ ESPRAZOLE ESPRAZOLE ESPRAZOLE ESPRAZOLE ESPRAZOLE ESPRAZOLE ES-AMAZOLE ES-AMAZOLE ES-AMAZOLE ES-AMAZOLE ESASIA ESASIA E-PRAZOLE E-PRAZOLE ACIFRE ARTEK ARTEK ACIFRE D AWA-BLOCK AWA-BLOCK ES-P ES-P ESOYAN ESOYAN ESOPRAL EGER EGER ESOGIP ESOGIP ESOGLIT ULCICARE ULCICARE GASTIZOL ESODIN ESODIN NAPZOL NAPZOL ZEXUM ZEXUM ZESPRA DIGESSO DIGESSO ESOX ESOX ESOT GASTROMEPRAZOLE ESOMEP ESOMEP ESOMAP ESOMAP RELAXUL RELAXUL S-ZOLE S-ZOLE PROTONIC ACTIF ACTIF MEPRIUM-L MEPRIUM MEPRIUM GASTROZOLE GASTROZOLE EMAGE EMAGE ESOZOLE ESOZOLE SHAEZ SHAEZ AMES AMES EPIM EPIM OTTOZOLE OTTOZOLE OTTOZOLE-T OTTOZOLE-T X-PRAZOLE X-PRAZOLE X-PRAZOLE X-PRAZOLE X-PRAZOLE NAVIX S-MEPRA EZZO EZZO ESONORM ESONORM HEALSO ESRO ESRO PURPAL PURPAL PURPAL VOGUE VOGUE CARAMEP CARAMEP GUDU 20 ELEPH ELEPH ULTECH ULTECH ESOZEF ESOGOOD ESOGOOD ESONIL ESONIL C-ESO C-ESO UTIL UTIL LEGRACE LEGRACE ESOTONE ESOTONE ESTONE SOLAZE ROCID-E ROCID-E S OM S OM ESOROL ESOROL ESIM ESIM ESIM ESIM ESOBORN ESOBORN ESOBORN ESOMEPRIN ESOMEPRIN ESZOLE TABLET ESZOLE TABLET ESODAY ESODAY GASTROLUX GASTROLUX LINSO HULERIC HULERIC ESOSIVE ESOSIVE LESOMEP ZOLISS ESOWEL MEPRAZ ESSOFASS ARLEC ARLEC S-MARK SAF-ESO SAF-ESO STOMWELL STOMWELL ESOFINE ESOFINE ESMOLEC ESMOLEC OMEGAST RAYNEX RAYNEX SYZAZOLE RAYPRAZOLE RAYPRAZOLE ESOR ESOR ESMEP ESMEP EMESS EMESS ESORANT ESORANT INTEZOLE ZOOM ZOOM KONCEPT KONCEPT KONCEPT S-PRAZOLE S-PRAZOLE SABIZOLE EPRAZIN EPRAZIN ESZOLE CAPSULE RECIPER ESOLE ES-BASOLE SOZO SOZO ESHO ESHO ESIAM ESIAM WINCID ESOBRAIN ROMEZOLE ROMEZOLE WESOPRAZOL WESOPRAZOL ESOLONE ESOLONE MEPREX MEPREX ESOLD ESOLD PROTX PROTX LOMAC LOMAC PROCAP PROCAP SIMESO SIMESO MAXPRO MAXPRO PEPSO USAN USAN
Adult Dose
Dose: IV-Inj
Single Dose: Continue until oral administration possible.
Frequency:
Route:
Instructions:
Neonatal
Paedriatic
Characteristics
Esomeprazole Magnesium trihydrate is the derivative of Esomeprazole. It is of Synthetic origin and belongs to Sulphinyl Benzimidazol. . The Molecular Weight of Esomeprazole is 345.40.
Contraindications
Esomeprazole is contraindicated in conditions like Hypersensitivity to the drug.
Effects
The severe or irreversible adverse effects of Esomeprazole, which give rise to further complications include Liver damage.The symptomatic adverse reactions produced by Esomeprazole are more or less tolerable and if they become severe, they can be treated symptomatically, these include Flatulence, Dizziness, Headache, Fatigue, Diarrhea, Myalgia, Constipation, Abdominal pain, Dry mouth, Blurred vision, Rashes, Pruritus, Malaise, Arthralgia, Nausea and vomiting, Musculoskeletal pain, Dry mouth, dizziness, subacute myopathy, athralgia.
Indications
Esomeprazole is primarily indicated in conditions like Gastric ulcer, Gastro-esophageal reflux disease, NSAID-associated ulceration, Zollinger-ellison syndrome, and can also be given in adjunctive therapy as an alternative drug of choice in Pernicious anaemia and other macrocytic anaemias.
Interactions
Esomeprazole is known to interact with other drugs, the details of drug interactions is as follows:DrugDetailsSeverityOnsetManagementCeftibutenClopidogrelDisulfiramCoadministration results in toxicityPhenytoin (Na)Esomeprazole decrease clearance of phenytoin by inhibiting CYP450Warfarin (Na)Esomeprazole decrease the clearance of diazepam by inhibiting CYP450 These interactions are sometimes beneficial and sometimes may pose threats to life. Always consult your physician for the change of dose regimen or an alternative drug of choice that may strictly be required.
Interfrence
Risks
Drug should not be given to Paediatrics, Pregnant Mothers, Geriatrics, and Neonates.If prescribing authority justifies the benefits of the drug against the possible damages he/she should reevaluate them and consult the reference material and previous studies.
Storage
Store at room temperature, . Protect from Sunlight.
Warnings
Esomeprazole should be given with caution in patients with renal impairment, liver disease, in pregnancy and in breast-feeding. Proton-pump inhibitors may mask symptoms of gastric cancer, particular care is required in those whose symptoms change and in those over 45 years of age; the presence of gastric malignancy should be excluded before treatment.
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