Eptifibatide

Eptifibatide is an antiplatelet drug that inhibits glycoprotein II b/ III a. Eptifibatide is used intravenously in the management of unstable angina and in patients undergoing angioplastic coronary interventions. In the latter case, the events of myocardial infarction or death have been reduced to 20%.


Adult Dose
Dose: 180 mcg/kg
Single Dose: 180 (180)
Frequency: As recommended.
Route: IV
Instructions: This loading dose of is given over 1 to 2 minutes immediately after diagnosis, followed by continuous i.v.-infusion of 2µg/kg and minute until either hospital discharge or initiation of coronary artery bypass grafting, or for up to 72 hours. At least 4 hours before discharge all local or systemic bleedings should have been controlled and terminated.
Neonatal
Paedriatic
Characteristics
belongs to Antiplatelet agents. . The Molecular Weight of Eptifibatide is 831.96.
Contraindications
Eptifibatide is contraindicated in conditions like Stroke,Severe hypotension,Hypersensitivity to the drug.
Effects
The severe or irreversible adverse effects of Eptifibatide, which give rise to further complications include Hypotension, Hypotension, Inflamation of vein.The signs and symptoms that are produced after the acute overdosage of Eptifibatide include Severe bleeding.The symptomatic adverse reactions produced by Eptifibatide are more or less tolerable and if they become severe, they can be treated symptomatically, these include Anemia, Bleeding, Allergic reaction.
Indications
Eptifibatide is primarily indicated in conditions like Acute coronary syndrome (without st-segment elevation), Blood clot, Myocardial infarction, Unstable angina.
Interactions
No data regarding the interactions of Eptifibatide was found.
Interfrence
Serum test for Creatinine and Glucose Hematocrit Value
Risks
Drug should not be given to Paediatrics.If prescribing authority justifies the benefits of the drug against the possible damages he/she should reevaluate them and consult the reference material and previous studies.
Storage
Warnings
Because eptifibatide keeps your blood from coagulating (clotting) to prevent unwanted blood clots, it can also make it easier for you to bleed, even from a minor injury. Contact your doctor or seek emergency medical attention if you have bleeding that will not stop. This medicine is for injection into a vein. It is usually given by a health care professional in a hospital or clinic setting. Talk to your pediatrician regarding the use of this medicine in children. Special care may be needed.
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