Dose: 0.357 to 0.428 mg/kg
Single Dose: 0.39 (0.3925)
Frequency: 8 hourly
Route: IM
Instructions: -

Dose: 0.5 to 1 mg/kg
Single Dose: 0.75 (0.75)
Frequency: 24 hourly
Route: usaual single dose to a total of 100mg/day (over age 6}.
Instructions:

Chlorprothixene also known as Alpha-chlorprothixiene, Alpha-chlorprothixiene, Alpha-chlorprothixiene. . It is of Synthetic origin and belongs to Thioxanthene. It belongs to D2 antagonist pharmacological group on the basis of mechanism of action and also classified in Psychotherapeutic Drugs and Antipsychotic Agent pharmacological group.The Molecular Weight of Chlorprothixene is 315.90. Its pKa is 8.4.

Chlorprothixene is contraindicated in conditions like Circulatory collapse,Coma.

The severe or irreversible adverse effects of Chlorprothixene, which give rise to further complications include Tardive dyskinesia, Seizures, Systemic lupus erythematosus.Chlorprothixene produces potentially life-threatening effects which include Obstructive Jaundice, Neuroleptic Malignant Syndrome, Neuroleptic malignant syndrome. which are responsible for the discontinuation of Chlorprothixene therapy.The signs and symptoms that are produced after the acute overdosage of Chlorprothixene include Hypotension, Tachycardia, Cardiac arrhythmias, Seizures, Cardiodepression, Respiratory arrest, Reduced peristalsis of GIT, Acute oliguria.The symptomatic adverse reactions produced by Chlorprothixene are more or less tolerable and if they become severe, they can be treated symptomatically, these include Skin rashesX, Sedation, Parkinsonism, Akathisia, Hypotension, Nausea and vomiting, Acute dystonia, Induction of hostility, Extra pyramidal symptoms.

Chlorprothixene is primarily indicated in conditions like Agitation, Mania, Psychosis, Schizophrenia, and can also be given in adjunctive therapy as an alternative drug of choice in Anxiety, Herpetic neuralgia.

No data regarding the interactions of Chlorprothixene was found.

Drug should not be given to Pregnant Mothers, Geriatrics, and Neonates.If prescribing authority justifies the benefits of the drug against the possible damages he/she should reevaluate them and consult the reference material and previous studies.

Tab Store in a well closed container, Below 40°C. Do not Freeze. Protect from Sunlight and Moisture.

Chlorprothixene should be used with caution in patients exposed to extreme heat or phosphorus insecticides, patients in state of alcohol withdrawal, patients with history of peptic ulcer, allergic reactions, with renal impairment, prostatic hypertrophy. Photosensitization may occur, caution patients to take appropriate measure (e.g.wear protective clothing or sunscreen) against exposure to sunlight or UV light. Discontinue use atleast 48 hours before myelography.