Dose: 150 mcg/kg of body weight
Single Dose: 150 (150)
Frequency: As recommended.
Route: IV
Instructions: Followed after initial dose

Lepirudin also known as Hirudin, Hirudin. . It is of Semi Synthetic origin. . The Molecular Weight of Lepirudin is 6979.50. It is weakly acidic drug.

Lepirudin is contraindicated in conditions like Pregnancy,Breast feeding.

The severe or irreversible adverse effects of Lepirudin, which give rise to further complications include Bleeding, Hematoma, Hematoma, Hypersensitivity.Lepirudin produces potentially life-threatening effects which include Intracranial hemorrhages. which are responsible for the discontinuation of Lepirudin therapy.The signs and symptoms that are produced after the acute overdosage of Lepirudin include Bleeding complications.The symptomatic adverse reactions produced by Lepirudin are more or less tolerable and if they become severe, they can be treated symptomatically, these include Fever, Hematuria, Allergic reactions, Rectal bleeding, Anemia.

Lepirudin is primarily indicated in conditions like Endometrial thinning before intra-uterine surgery.

No data regarding the interactions of Lepirudin was found.

Drug should not be given to Paediatrics, and Pregnant Mothers.If prescribing authority justifies the benefits of the drug against the possible damages he/she should reevaluate them and consult the reference material and previous studies.

Renal impairment; hepatic impairment; recent bleeding or risk of bleeding including recent puncture of large vessels, organ biopsy, recent major surgery, stroke, haemorrhagic diathesis, severe uncontrolled hypertension, bacterial endocarditis; determine activated partial thromboplastin time 4 hrs after start of treatment (or after infusion rate altered) and at least once daily thereafter.