Chloral Betaine

Chloral Betaine is used in the short-term management of insomnia. It dissociates in the stomach to release chloral hydrate, therefore, has actions and uses similar to those of chloral hydrate.


Brands
Adult Dose
Dose: 700 to 1400 mg
Single Dose: 1000 (1050)
Frequency: 24 hourly
Route: PO
Instructions: Should be taken 15-30 min before bed time.
Neonatal
Paedriatic
Characteristics
Chloral Betaine also known as Cloral betaine. . It is of Synthetic origin and belongs to Chloral hydrate betaine. . The Molecular Weight of Chloral Betaine is 282.60.
Contraindications
Chloral Betaine is contraindicated in conditions like Renal failure,Gastritis,Hepatic failure,Cardiac disease,Porphyria.
Effects
The severe or irreversible adverse effects of Chloral Betaine, which give rise to further complications include Bradycardia, Eosinophilia, CNS depression, Hypoprothorombinemia, Hepatic encephalopathy exacerbation.Chloral Betaine produces potentially life-threatening effects which include Hepatic coma, Leukopenia. which are responsible for the discontinuation of Chloral Betaine therapy.The signs and symptoms that are produced after the acute overdosage of Chloral Betaine include Cardiac arrhythmias, Coma, Ataxia, Respiratory depression, Lethargy.The symptomatic adverse reactions produced by Chloral Betaine are more or less tolerable and if they become severe, they can be treated symptomatically, these include Drowsiness, Confusion, Skin RashX, GI symptoms, Disorientation.
Indications
Chloral Betaine is primarily indicated in conditions like Insomnia, Postoperative sedation, Pre-operative sedation.
Interactions
No data regarding the interactions of Chloral Betaine was found.
Interfrence
Assay of Glucose (Benedics Test), Steroids and Urea
Risks
Drug should not be given to Pregnant Mothers, Cardiac / Hypertensive Patients, patients suffering from Kidney dysfunction, patients suffering from Liver Malfunction, and Neonates.If prescribing authority justifies the benefits of the drug against the possible damages he/she should reevaluate them and consult the reference material and previous studies.
Storage
Tabs Store in a well closed container, . Protect from Sunlight, Moisture and Heat.
Warnings
Patients should observe caution while driving or performing other tasks requiring alertness, because it may cause drowsiness. Do not use in larger doses in patients with severe cardiac disease. Exercise caution in administering to patients prone to addiction. It should be used with caution (if contains tartrazine) in patients with aspirin hypersensitivity, because may produced allergic reaction (including bronchial asthma).
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