Brimonidine (Tartrate)

Brimonidine (Tartrate) is an alpha-2 adrenoceptor stimulant. Brimonidine (Tartrate) is used topically to lower the intra-ocular pressure (IOP) in open angle glaucoma or ocular hypertension in patients for whom beta-blockers are inappropriate or may be given as an adjunct to beta-blocker.

Brands
ALPHAGAN BRIMONIDINE TARTRATE COMBIGAN ONIDIN BRIMOLOL
Adult Dose
Dose: 1 drop
Single Dose: 1 (1)
Frequency: 8 hourly
Route: Opthalmic
Instructions: For open angle galucoma/Occular hypertension
Neonatal
Paedriatic
Characteristics
. It is of Synthetic origin. . The Molecular Weight of Brimonidine (Tartrate) is 442.20. It is weakly acidic drug.
Contraindications
Brimonidine (Tartrate) is contraindicated in conditions like Hypersensitivity to the drug.
Effects
The symptomatic adverse reactions produced by Brimonidine (Tartrate) are more or less tolerable and if they become severe, they can be treated symptomatically, these include Headache, Dry mouth, Blurred vision, Taste disturbance, Asthenia, Mydriasis, Ocular irritation, Hyperemia, Lid retraction, Conjunctival bleeding, Increased tearing, Lids edema.
Indications
Brimonidine (Tartrate) is primarily indicated in conditions like Ocular hypertension, Open-angle glaucoma.
Interactions
No data regarding the interactions of Brimonidine (Tartrate) was found.
Interfrence
Risks
Drug should not be given to Paediatrics.If prescribing authority justifies the benefits of the drug against the possible damages he/she should reevaluate them and consult the reference material and previous studies.
Storage
Drops Store Below 30°C. Protect from Sunlight and Heat.
Warnings
It should be used with caution in patients with depression, cerebral or coronary insufficiency, raynauds phenomenon, orthostatic hypotension, severe cardiovascular disease and hepatic or renal impairment. Donot use in patients receiving mono amino oxidase inhbitors.
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