BONEFOS BONEFOS

Dose: 800 mg
Single Dose: 800 (800)
Frequency: 12 hourly
Route: PO
Instructions: The capsules should be taken with a little fluid, but not milk, at least 1 hour before or 1 hour after food. If necessary, the dose may be increased but should not exceed a maximum of 3200 mg sodium clodronate daily.

Sodium Clodronate also known as Clodronic Acid, Clodronic Acid, Clodronic Acid, Clodronic Acid. . It is of Synthetic origin and belongs to Biphosphonate. . The Molecular Weight of Sodium Clodronate is 360.90. Its pKa is 1.0 , 1.8, 6, 9.5.

Sodium Clodronate is contraindicated in conditions like Renal insufficiency.

Sodium Clodronate produces potentially life-threatening effects which include Acute Renal Failure. which are responsible for the discontinuation of Sodium Clodronate therapy.The signs and symptoms that are produced after the acute overdosage of Sodium Clodronate include Acute renal failure.The symptomatic adverse reactions produced by Sodium Clodronate are more or less tolerable and if they become severe, they can be treated symptomatically, these include Nausea, Vomiting, Flushing, Hypocalcemia.

Sodium Clodronate is primarily indicated in conditions like Hypercalcaemia, Hypercalcaemia associated with malignancy, Hypercalcaemia of malignancy, Osteolytic bone metastases, Osteolytic lesions.

No data regarding the interactions of Sodium Clodronate was found.

Drug should not be given to Paediatrics, Pregnant Mothers, and Neonates.If prescribing authority justifies the benefits of the drug against the possible damages he/she should reevaluate them and consult the reference material and previous studies.

Inj, caps Store at room temperature, . Protect from Sunlight, Moisture and Heat.

Adequate fluid intake must be maintained during sodium clodronate treatment. This is particularly important when administering sodium clodronate as intravenous infusion and in patients with hypercalcemia or renal failure. Intravenous administration of doses notably higher than those recommended may cause severe renal damage especially if the infusion rate is too high.