HUMALOG HUMALOG MIX 25 HUMALOG MIX 25 HUMALOG MIX 50

Dose: 0.5 to 1.2 units/kg/day
Single Dose: 0.85 (0.85)
Frequency: As recommended.
Route: SC
Instructions: The dosage of insulin lispro must be individualized. Blood glucose monitoring is essential in all patients receiving insulin _x000D_therapy._x000D_It may be administered by continuous subcutaneous infusion by an external insulin pump. Do not use diluted or mixed insulins in external insulin pumps. Infusion sites should be rotated within the same region to reduce the risk of lipodystrophy . Change insulin lispro in the reservoir at least every 7 days, change the infusion sets and the infusion set insertion site at least every 3 days.

. It is of Semi Synthetic origin and belongs to Polypeptide. . The Molecular Weight of Insulin Lispro is 5808.00. It is weakly alkaline drug.

Insulin Lispro is contraindicated in conditions like Hypoglycaemia,Hypersensitivity to any component of product.

The severe or irreversible adverse effects of Insulin Lispro, which give rise to further complications include Wheezing, Hypoglycemia, Hives, Lipoatrophy, Muscle Cramps, Difficulty in breathing.The symptomatic adverse reactions produced by Insulin Lispro are more or less tolerable and if they become severe, they can be treated symptomatically, these include Headache, Constipation, Peripheral edema, Pharyngitis, Allergic reactions, Redness, Cough, Rhinitis, Swelling at injection site, Infection, Swelling of feet.

Insulin Lispro is primarily indicated in conditions like Iddm, Type II diabetes mellitus.

Insulin Lispro is known to interact with other drugs, the details of drug interactions is as follows:DrugDetailsSeverityOnsetManagementAlcoholAmitriptyline (HCl)AspirinHypoglycaemic effect of insulin may be potentiated by aspirin by stimulating secretion of insulin.ModerateClosely monitor the development of hypoglycemia particularly in advanced age or renally impaired patient. Dose of insulin should be adjusted accordingly.Chlordiazepoxide (HCl)Chlorpromazine (HCl)Clonidine (HCl)DanazolDiazoxideDiltiazem (HCl)DisopyramideFenfluramine (HCl)GuanethidineLithiumMebendazoleNifedipineOctreotide (Acetate)Pentoxifylline These interactions are sometimes beneficial and sometimes may pose threats to life. Always consult your physician for the change of dose regimen or an alternative drug of choice that may strictly be required.

Monitoring of blood and urine glucose

If prescribing authority justifies the benefits of the drug against the possible damages he/she should reevaluate them and consult the reference material and previous studies.

Hypoglycemia is the most common adverse effect associated with insulins, including insulin lispro. As with all insulins, the timing of hypoglycemia may differ among various insulin formulations. Glucose monitoring is recommended for all patients with diabetes. Any change of insulin should be made cautiously and only under medical supervision. The requirements for insulin may be reduced in patients with renal impairment. Although impaired hepatic function does not affect the absorption or disposition of insulin lispro, careful glucose monitoring and dose adjustments of insulin, including Humalog, may be necessary.