Celecoxib

Celecoxib is an NSAID, a selective inhibitor of cyclo-oxygenase-2 (COX-2). Celecoxib is used in the treatment of rheumatoid arthritis and osteoarthritis. It is also used for ankylosing spondylitis.


Adult Dose
Neonatal
Paedriatic
Dose: 5 mg
Single Dose: 5 (5)
Frequency: 12 hourly
Route: for childeren behaving 10 to 25kg
Instructions:
Characteristics
. It is of Synthetic origin and belongs to NSAID. . The Molecular Weight of Celecoxib is 381.40.
Contraindications
Celecoxib is contraindicated in conditions like Asthma,Urticaria,Hypersensitivity.
Effects
The severe or irreversible adverse effects of Celecoxib, which give rise to further complications include Hepatotoxicity, Gi bleeding, Rhinitis, GI bleeding, Rhinitis, Hepatotoxicity, Myalgia, Urinary tract infection, Bronchitis, Pharyngitis.Celecoxib produces potentially life-threatening effects which include Myocardial infarction, Hypotension, Heart failure, Death. which are responsible for the discontinuation of Celecoxib therapy.The symptomatic adverse reactions produced by Celecoxib are more or less tolerable and if they become severe, they can be treated symptomatically, these include Flatulence, Dizziness, Headache, Nausea, Vomiting, Diarrhea, Constipation, Insomnia, Abdominal pain, Rashes, Pruritus, Dyspepsia, Cough, Edema, dizziness, dyspepsia.
Indications
Celecoxib is primarily indicated in conditions like Ankylosing spondylitis, Osteoarthritis, Rheumatoid arthritis, and can also be given in adjunctive therapy as an alternative drug of choice in Dysmenorrhoea, Pain, Toothache.
Interactions
No data regarding the interactions of Celecoxib was found.
Interfrence
Risks
Drug should not be given to Pregnant Mothers, patients suffering from Kidney dysfunction, and Neonates.If prescribing authority justifies the benefits of the drug against the possible damages he/she should reevaluate them and consult the reference material and previous studies.
Storage
Caps Store in a well closed container, Between 20°C-25°C. Protect from Moisture and Heat.
Warnings
It is classifed as pregnancy category C, and should be used with caution during pregnancy only if clearly needed. Avoid use in case of hypersensitivity to celecoxib or any component, sulfonamides, aspirin or other non steroidal anti-inflammatory drugs.
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