APNOTEK CEDATE CHLORAL HYDRATE CHLORAL HYDRATE

Dose: 500 to 1000 mg
Single Dose: 750 (750)
Frequency: 24 hourly
Route: PO
Instructions: Usually taken 30 min before bed time

Dose: 30 to 50 mg/kg
Single Dose: 40 (40)
Frequency: 8 hourly
Route: oral
Instructions: up to 100mg/kg maximum of 3 g may be used with respiratiry monitrng.

Dose: 0.5 to 1 g
Single Dose: 0.75 (0.75)
Frequency: 8 hourly
Route: Oral
Instructions: 12 year to 18 year up to 100mg/kg maximum of 3 g may be used with respiratiry monitrng.

. It is of Synthetic origin and belongs to Chloroethane. It belongs to Hypnotic pharmacological group on the basis of mechanism of action and also classified in sedative pharmacological group.The Molecular Weight of Chloral Hydrate is 165.40. Its pKa is 10.

Chloral Hydrate is contraindicated in conditions like Renal failure,Gastritis,Hepatic failure,Cardiac disease,Porphyria.

The severe or irreversible adverse effects of Chloral Hydrate, which give rise to further complications include Bradycardia, Eosinophilia, Eosinophilia, Liver cirrhosis, CNS depression, Hypoprothorombinemia, Hepatic encephalopathy exacerbation.Chloral Hydrate produces potentially life-threatening effects which include Hepatic coma, Drowsiness, Semicoma. which are responsible for the discontinuation of Chloral Hydrate therapy.The signs and symptoms that are produced after the acute overdosage of Chloral Hydrate include Cardiac arrhythmias, Coma, Respiratory depression, Ataxia, Lethargy.The symptomatic adverse reactions produced by Chloral Hydrate are more or less tolerable and if they become severe, they can be treated symptomatically, these include Headache, Drowsiness, Ataxia, Confusion, Pain, Skin RashX, Hallucination, Gastric irritation, Hypersensitivity, Disorientation, Nightmares, Confusion, Ataxia.

Chloral Hydrate is primarily indicated in conditions like Insomnia, Postoperative sedation, Pre-operative sedation, and can also be given in adjunctive therapy as an alternative drug of choice in Nausea, vertigo, labyrinthine disorders.

No data regarding the interactions of Chloral Hydrate was found.

Assay of Glucose (Benedics Test), Steroids and Urea

Drug should not be given to Pregnant Mothers, Cardiac / Hypertensive Patients, patients suffering from Kidney dysfunction, patients suffering from Liver Malfunction, and Neonates.If prescribing authority justifies the benefits of the drug against the possible damages he/she should reevaluate them and consult the reference material and previous studies.

Suppositories, Caps Store in a well closed container, Below 40°C. Protect from Sunlight and Moisture. Syrup Store in a well closed container, at room temperature. Do not Freeze. Protect from Sunlight.

Patients should observe caution while driving or performing other tasks requiring alertness, because it may cause drowsiness. Do not use chloral hydrate in larger doses in patients with severe cardiac disease. Exercise caution in administering to patients prone to addiction. It should be used with caution (if contains tartrazine) in patients with aspirin hypersensitivity, because may produced allergic reaction (including bronchial asthma).