Hepatitis B Immunoglobulin

Hepatitis B Immunoglobulin is a sterile liquid freez-dried preparation containing immunoglobulins, mainly immunoglobulin G (IgG), derived from the plasma from selected immunised donors having specific antibodies against hepatitis B surface antigen. Hepatitis B immunoglobulins are used for the passive immunisation of persons expose or possibly exposed to hepititis B virus.

Brands
HYPERHEP B HYPERHEP B HEPATECT BEHRING HEPUMAN
Adult Dose
Dose: 0.06 ml/ kg
Single Dose: 0.06 (0.06)
Frequency: As recommended.
Route: IM
Instructions: As soon as possible after exposure. For Perinatal exposure, Give within 12 hours after birth.
Neonatal
Paedriatic
Characteristics
. It is of Natural origin. .
Contraindications
Hepatitis B Immunoglobulin is contraindicated in conditions like Hypersensitivity.
Effects
The symptomatic adverse reactions produced by Hepatitis B Immunoglobulin are more or less tolerable and if they become severe, they can be treated symptomatically, these include Headache, Nausea, Fever, Chills, Facial flushing, Hypersensitivity.
Indications
Hepatitis B Immunoglobulin is primarily indicated in conditions like Prevention of hepatitis B, after exposure.
Interactions
No data regarding the interactions of Hepatitis B Immunoglobulin was found.
Interfrence
Misleading + results in serological testingInterferes with serological tests for red cell anti bodies e.g coombs test.
Risks
Drug should not be given to Pregnant Mothers.If prescribing authority justifies the benefits of the drug against the possible damages he/she should reevaluate them and consult the reference material and previous studies.
Storage
IM Inj Store in a well closed container, Below 15°C. Do not Freeze. Protect from Sunlight.
Warnings
It should be used with caution in patients with any pre-existing illnesses, blood disorders or any allergy, including any drug allergy. It should be used only when clearly needed during pregnancy. Pateints should be manitored for serum anti-HBS antibody levels regularly.
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