Norgestimate

Norgestimate is a progestogen structurally related to levonorgestrel. Norgestimate is used as a part of progestogenic part of combined oral contraceptives.


Brands
Adult Dose
Dose: 1 tab
Single Dose: 1 (1)
Frequency: 24 hourly
Route: PO
Instructions:
Neonatal
Paedriatic
Characteristics
. It is of Synthetic origin and belongs to Progestogen. . The Molecular Weight of Norgestimate is 369.50.
Contraindications
Norgestimate is contraindicated in conditions like Breast cancer,Circulatory system disease,Liver diseases,Genital bleeding,Disturbance of lipid metabolism.
Effects
The severe or irreversible adverse effects of Norgestimate, which give rise to further complications include Hypertension.Norgestimate produces potentially life-threatening effects which include Venous thromboembolism, Ischemic heart disease, Cerebrovascular disease. which are responsible for the discontinuation of Norgestimate therapy.The signs and symptoms that are produced after the acute overdosage of Norgestimate include Nausea, Vomiting, Vaginal bleeding.The symptomatic adverse reactions produced by Norgestimate are more or less tolerable and if they become severe, they can be treated symptomatically, these include Headache, Nausea, Weight gain, Acne, Depressive moods, Changes in libido.
Indications
Norgestimate is primarily indicated in conditions like Oral contraception.
Interactions
No data regarding the interactions of Norgestimate was found.
Interfrence
Serum Tests for Adrenal Corticosteroids Urine Tests for 17-Ketosteroids and 17-OH Corticosteroids and Aldosterone Thyopac Method for Measurement of T3
Risks
Drug should not be given to Paediatrics, Cardiac / Hypertensive Patients, patients suffering from Liver Malfunction, and Neonates.If prescribing authority justifies the benefits of the drug against the possible damages he/she should reevaluate them and consult the reference material and previous studies.
Storage
Store in a well closed container. Tab Protect from Sunlight.
Warnings
It should be used with caution in patients with any allergy (especially drug allergy), abnormal vaginal bleeding, liver, kidney or heart disease, cancer of the breast or genitals, missed abortion, blood clots, seizures, migraine, asthma, depression or diabetes. Limit alcohol, as this may increase side effects of this drug. It shold be used with caution while performing tasks requiring mental alertness (e.g.driving) as this drug may cause drowsiness.
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