Troglitazone

An oral hypoglycemic used for the treatment of type-II diabetes mellitus. Troglitazone has been associated with severe hepatic reactions, which has led to the withdrawal of this drug in the UK.

Brands
Adult Dose
Neonatal
Paedriatic
Characteristics
. It is of Synthetic origin. . The Molecular Weight of Troglitazone is 441.50. Its pKa is 6.1, 12.
Contraindications
Troglitazone is contraindicated in conditions like Diabetes mellitus,Hypersensitivity,Pregnancy.
Effects
The symptomatic adverse reactions produced by Troglitazone are more or less tolerable and if they become severe, they can be treated symptomatically, these include Headache, Fatigue, Nausea, Vomiting, Diarrhea, Malaise, Musculoskeletal pain.
Indications
Troglitazone is primarily indicated in conditions like Diabetes insipidus.
Interactions
No data regarding the interactions of Troglitazone was found.
Interfrence
Risks
Drug should not be given to Paediatrics, and Pregnant Mothers.If prescribing authority justifies the benefits of the drug against the possible damages he/she should reevaluate them and consult the reference material and previous studies.
Storage
Tab Store Between 20°C-25°C. Protect from Moisture.
Warnings
It should be used with caution in patients with heart failure. Regular monitoring of liver function during therapy and withdrawal of drug in any patient who develops jaundice or sign of liver dysfunction is required.
Back to List

Any information that appears on this website page is provided for the purpose of general information. This website has been compiled in good faith by HMIS.Online. However, no guarantee is made as to the completeness, validity or accuracy of the information it contains.