Diprophylline

Diprophylline is a derivative of theophyline, used as a bronchodilator. The action and uses are similar to those of theophyline.


Brands
Adult Dose
Dose: 15 mg/kg of body weight
Single Dose: 15 (15)
Frequency: 6 hourly
Route: PO
Instructions:
Neonatal
Paedriatic
Characteristics
. It is of Synthetic origin. . The Molecular Weight of Diprophylline is 254.20. It is weakly acidic drug.
Contraindications
Diprophylline
Effects
The severe or irreversible adverse effects of Diprophylline, which give rise to further complications include Convulsions, Cardiac arrhythmias, Hypotension, Gynecomastia.The signs and symptoms that are produced after the acute overdosage of Diprophylline include Hypotension, Death, Vomiting, Tachycardia, Cardiac arrhythmias, Hematemesis, Convulsions, Dehydration, Diuresis, Agitation.The symptomatic adverse reactions produced by Diprophylline are more or less tolerable and if they become severe, they can be treated symptomatically, these include Dizziness, Headache, Diarrhea, Anxiety, Restlessness, Palpitation, Insomnia, Abdominal pain, Tremor, Nausea and vomiting, GI irritation.
Indications
Diprophylline is primarily indicated in conditions like Airway obstruction, Apnoea, Bronchospasm, and can also be given in adjunctive therapy as an alternative drug of choice in Asthma, Obstructive airway disease.
Interactions
No data regarding the interactions of Diprophylline was found.
Interfrence
Pulmonary function test
Risks
Drug should not be given to patients suffering from Kidney dysfunction.If prescribing authority justifies the benefits of the drug against the possible damages he/she should reevaluate them and consult the reference material and previous studies.
Storage
Tab, Cap, Inj Store in a well closed container. Protect from Sunlight.
Warnings
It should be use with caution in patients with severe cardiac, kidney or liver disease, hyperthyroidism, congestive heart failure (CHF), peptic ulcer. It should be use with caution in neonates and elderly persons.
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