Zotepine

An atypical antipsychotic, used to treat schizophrenia. It has less extrapyramidal symptoms as compared to old antipsychotics.


Brands
Adult Dose
Neonatal
Paedriatic
Characteristics
. It is of Synthetic origin and belongs to Dibenzothiepine. . The Molecular Weight of Zotepine is 331.87.
Contraindications
Zotepine is contraindicated in conditions like Cardiac arrhythmia,Hypertension,Convulsions,Hypotension,Narrow-angle glaucoma,Hypersensitivity,Intoxication with alcohol,Hematopoietic disorder,Urinary retention.
Effects
The severe or irreversible adverse effects of Zotepine, which give rise to further complications include Seizures.Zotepine produces potentially life-threatening effects which include Muscle rigidity, Neuroleptic Malignant Syndrome, Hyperpyrexia, Akinesia. which are responsible for the discontinuation of Zotepine therapy.The signs and symptoms that are produced after the acute overdosage of Zotepine include Hypotension, Tachycardia, Cardiac arrhythmias, Convulsions, Coma, Seizures, Respiratory depression, Hypothermia, Agitation, Cardiovascular collapse, Extrapyramidal effects.The symptomatic adverse reactions produced by Zotepine are more or less tolerable and if they become severe, they can be treated symptomatically, these include Dizziness, Headache, Fatigue, Tachycardia, Dry mouth, Sedation, Parkinsonism, Akathisia, Weight gain, Hot flushes, Respiratory depression, Extrapyramidal effects, Orthostatic hypotension, Dyskinesia.
Indications
Zotepine is primarily indicated in conditions like Schizophrenia, Schizophreniform psychoses.
Interactions
No data regarding the interactions of Zotepine was found.
Interfrence
Risks
Drug should not be given to Pregnant Mothers, patients suffering from Kidney dysfunction, patients suffering from Liver Malfunction, and Neonates.If prescribing authority justifies the benefits of the drug against the possible damages he/she should reevaluate them and consult the reference material and previous studies.
Storage
Tab
Warnings
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