Nicergoline

Nicergoline is an ergot derivative, which is used for the symtomatic treatment of mental deterioration associated with cerebrovascular insufficiency and in peripheral vascular disease. Nicergoline is given orally as well as parenterally.

Brands
Adult Dose
Dose: 5 to 10 mg
Single Dose: 7.5 (7.5)
Frequency: 8 hourly
Route: PO
Instructions:
Neonatal
Paedriatic
Characteristics
. It is of Synthetic origin and belongs to Ergot derovation. . The Molecular Weight of Nicergoline is 484.40. Its pKa is 8.4.
Contraindications
Nicergoline is contraindicated in conditions like Myocardial infarction,Bradycardia.
Effects
The signs and symptoms that are produced after the acute overdosage of Nicergoline include Severe hypotension.The symptomatic adverse reactions produced by Nicergoline are more or less tolerable and if they become severe, they can be treated symptomatically, these include Dizziness, Vertigo, Headache, Drowsiness, Nausea, Anorexia, Diarrhea, Constipation, Tinnitus, Abdominal pain, Dry mouth, Urticaria, Pruritus, Skin RashX, Malaise.
Indications
Nicergoline is primarily indicated in conditions like Mental sequelae of cerebrovascular disorder, Pruritus.
Interactions
No data regarding the interactions of Nicergoline was found.
Interfrence
Risks
Drug should not be given to Paediatrics, Pregnant Mothers, and Neonates.If prescribing authority justifies the benefits of the drug against the possible damages he/she should reevaluate them and consult the reference material and previous studies.
Storage
Tab, Powder Store in a well closed container, at room temperature. Protect from Sunlight.
Warnings
Although toxicology studies have not shown nicergoline to have any teratogenic effect, the use of this medicine during pregnancy should be limited to those cases where it is absolutely necessary.
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