Valaciclovir (HCl)

A pro-drug of acyclovir, used for herpes zoster and herpes simplex infections of the skin and mucous membranes, It is used for preventing cytomegalovirus diseases following renal transplantation. Non-dose-limiting confusion and hallucinations are the most frequent side effects.


Adult Dose
Neonatal
Paedriatic
Characteristics
. It is of Synthetic origin. . The Molecular Weight of Valaciclovir (HCl) is 360.80.
Contraindications
Valaciclovir (HCl)
Effects
The severe or irreversible adverse effects of Valaciclovir (HCl), which give rise to further complications include Thrombocytopenic purpura, Hemolytic uremic syndrome.The symptomatic adverse reactions produced by Valaciclovir (HCl) are more or less tolerable and if they become severe, they can be treated symptomatically, these include Dizziness, Headache, Nausea.
Indications
Valaciclovir (HCl) is primarily indicated in conditions like Herpes simplex, Herpes simplex infections, Herpes zoster, Prevention of cytomagalovirus disease, Prevention of cytomagalovirus disease (following renal transplantation), Prevention of cytomegalovirus disease, and can also be given in adjunctive therapy as an alternative drug of choice in Prevention of cytomagalo virus.
Interactions
No data regarding the interactions of Valaciclovir (HCl) was found.
Interfrence
Risks
If prescribing authority justifies the benefits of the drug against the possible damages he/she should reevaluate them and consult the reference material and previous studies.
Storage
Warnings
It should be used with caution in patients with renal impairment and doses should be adjusted accorging to creatinine clearance. This medication should be used with caution during pregnancy and lactation.
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