RICAS RICAS EPOZOLINE EPOZOLINE EPOZOLINE CEPZOLIN CEPZOLIN PEPKOL PEPKOL PEPKOL NELZIM NELZIM REFLIN REFLIN REFLIN FAZOLIN FAZOLIN FAZOLIN ZAFACAIN ZAFACAIN ZOLINEX ZOLINEX ZOLINEX CEFABIOT CEFABIOT RAVICEF RAVICEF RAVICEF SILZOLIN ARZOLIN ARZOLIN ARZOLIN NOZOGARD NOZOGARD NOZOGARD HIFAL LINCEF LINCEF LINCEF KEFLINE KEFLINE KEFLINE SWIFLIN SWIFLIN SWIFLIN ZOLICEF ZOLICEF ZOLICEF

Dose: 500 to 1000 mg
Single Dose: 750 (750)
Frequency: 6 hourly
Route: IV,IM
Instructions:

Dose:
Single Dose:
Frequency:
Route:
Instructions: Not recommended in this age group

Dose: 25 to 50 mg/kg
Single Dose: 38 (37.5)
Frequency: 8 hourly
Route: Intra Muscular
Instructions: Maximum of 100mg/kg.

Cephazolin is the derivative of Cephazolin (Na). It is of Semi Synthetic origin and belongs to Cephalosporin. It belongs to Peptidoglycan synthesis inhibitor pharmacological group on the basis of mechanism of action and also classified in Antibiotics pharmacological group.The Molecular Weight of Cephazolin (Na) is 476.50. Its pKa is 2.1.

Cephazolin (Na) is contraindicated in conditions like Pregnancy,Hypersensitivity to any component of product.

The severe or irreversible adverse effects of Cephazolin (Na), which give rise to further complications include Convulsions, Thrombocytopenia, Hypersensitivity reactions, Eosinophilia, Eosinophilia, Leucopenia, Neutropenia.Cephazolin (Na) produces potentially life-threatening effects which include Pseudomembranous colitis, Anaphylactic reactions. which are responsible for the discontinuation of Cephazolin (Na) therapy.The symptomatic adverse reactions produced by Cephazolin (Na) are more or less tolerable and if they become severe, they can be treated symptomatically, these include Nausea, Anorexia, Diarrhea, Genital and anal pruritus, Genital moniliasis, Transient rise in SGPT & SGOT, Rise in blood urea levels.

Cephazolin (Na) is primarily indicated in conditions like Bacterial infections, Bone and joint infection, Endocarditis, Genitourinary tract infections, Peritonitis, Persistant neutropenia in advanced hiv infection, Respiratory tract infections, Septicaemia, Skin infections, Soft tissue infections, and can also be given in adjunctive therapy as an alternative drug of choice in Biliary tract disorders, Bronchiectasis, Bronchogenic carcinoma, Pneumonia.

Cephazolin (Na) is known to interact with other drugs, the details of drug interactions is as follows:DrugDetailsSeverityOnsetManagementAlcoholPivmecillinam (HCl)Simultaneous administration of other Cephazolin (Na) with Pivmecillinam (HCl) Tablets may produce a synergistic effect.Probenecid These interactions are sometimes beneficial and sometimes may pose threats to life. Always consult your physician for the change of dose regimen or an alternative drug of choice that may strictly be required.

False +ve Coombs Test Reversed phase HPLC method for the analysis of theophylline Positve Coombs test, interfere with cross matching of Blood False + ve reaction to benedicts & fehling reagents

Drug should not be given to Paediatrics, Pregnant Mothers, patients suffering from Kidney dysfunction, and Neonates.If prescribing authority justifies the benefits of the drug against the possible damages he/she should reevaluate them and consult the reference material and previous studies.

Inj Store Below 40°C. Protect from Sunlight.

Cephazolin should be used with caution in patients with impaired kidney or liver function. Appropriate measure should be taken if secondary infection occurs. It should be used with caution (if contains tartrazine) in patients with aspirin hypersensitivity, because it may cause allergic reactions (including bronchial asthma).