Sevoflurane

Sevoflurane is a volatile halogenated anesthetic. Sevoflurane is administered by inhalation using a calibrated vaporizer. Sevoflurane is employed for induction and maintenance of general anesthesia. It has a rapid onset of action and recovery. It possesses muscle relaxant properties, however having no analgesic properties.

Brands
SEVORANE
Adult Dose
Dose: 5 % v/v
Single Dose: 5 (5)
Frequency: As recommended.
Route: Inhalation
Instructions: With oxygen or oxygen and nitrous oxide.
Neonatal
Paedriatic
Characteristics
. It is of Synthetic origin. . The Molecular Weight of Sevoflurane is 200.10.
Contraindications
Sevoflurane is contraindicated in conditions like Pregnancy,Lactation.
Effects
The severe or irreversible adverse effects of Sevoflurane, which give rise to further complications include Hypotension, Myocardial depression, Cardiovascular collapse, Malignant hyperthermia.Sevoflurane produces potentially life-threatening effects which include Malignant pyrexia. which are responsible for the discontinuation of Sevoflurane therapy.The signs and symptoms that are produced after the acute overdosage of Sevoflurane include Depression of vital functions.The symptomatic adverse reactions produced by Sevoflurane are more or less tolerable and if they become severe, they can be treated symptomatically, these include Nausea and vomiting, Shivering.
Indications
Sevoflurane is primarily indicated in conditions like Induction and maintenance of anaesthesia, Induction of anaesthesia, Maintenance of anaesthesia.
Interactions
Sevoflurane is known to interact with other drugs, the details of drug interactions is as follows:DrugDetailsSeverityOnsetManagementAdrenalineAtracurium (Besylate)IsoniazidIsoproterenolMivacurium (Cl) These interactions are sometimes beneficial and sometimes may pose threats to life. Always consult your physician for the change of dose regimen or an alternative drug of choice that may strictly be required.
Interfrence
Risks
If prescribing authority justifies the benefits of the drug against the possible damages he/she should reevaluate them and consult the reference material and previous studies.
Storage
Inhaler Store in a well closed container, at room temperature. Protect from Heat.
Warnings
It should be given with caution in patients with hypovolumia, epilapsy, lipid metabolism disorder, and in elderly. It should not be used with electroconvulsive therapy. It is not recommended as an anesthatic in children under 3yrs of age.
Back to List

Any information that appears on this website page is provided for the purpose of general information. This website has been compiled in good faith by HMIS.Online. However, no guarantee is made as to the completeness, validity or accuracy of the information it contains.