Trimethobenzamide (HCl)

A dopamine blocker , which has weak antihistaminic activity. It is given for the treatment and prevention of nausea and vomiting. Major adverse effects include restlessness, dystonia, and parkinsonian symptoms.

Brands
Adult Dose
Neonatal
Paedriatic
Characteristics
. It is of Synthetic origin. . The Molecular Weight of Trimethobenzamide (HCl) is 424.90.
Contraindications
Trimethobenzamide (HCl)
Effects
The severe or irreversible adverse effects of Trimethobenzamide (HCl), which give rise to further complications include Convulsions, Cardiac arrhythmias, CNS depression, Paresthesia, Blood disorders.The symptomatic adverse reactions produced by Trimethobenzamide (HCl) are more or less tolerable and if they become severe, they can be treated symptomatically, these include Headache, Diarrhea, Dry mouth, Blurred vision, Nausea and vomiting, Epigastric pain, Bronchospasm, Local irritation, Angioedema, Pain at injection site.
Indications
Trimethobenzamide (HCl) is primarily indicated in conditions like Nausea and vomiting.
Interactions
Trimethobenzamide (HCl) is known to interact with other drugs, the details of drug interactions is as follows:DrugDetailsSeverityOnsetManagementAtropine (Sulphate)ClemastineGlycopyrrolate These interactions are sometimes beneficial and sometimes may pose threats to life. Always consult your physician for the change of dose regimen or an alternative drug of choice that may strictly be required.
Interfrence
Risks
If prescribing authority justifies the benefits of the drug against the possible damages he/she should reevaluate them and consult the reference material and previous studies.
Storage
Cap, Inj
Warnings
It should be used with caution in patients with any eye problems, high blood pressure, diabetes, thyroid disorder, heart disease, asthma or allergies, especially to sulfites. Use with caution during pregnancy or lactation.
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