Cephalexin (Monohydrate)

Cephalexin is a first generation cephalosporin antibiotic. Cephalosporins are derivatives of 7-aminocephalosporic acid and are closely related to penicillin in structure. Cephalosporins have a six membered sulfur containing ring adjoining a β lactam ring. Cephalexin is very active against gram positive cocci and used in a large variety of bacterial infections, such as respiratory tract, skin and urinary tract infections. Antibiotics require constant drug level in body for therapeutic effect. This is achieved by taking the medication at regular interval of time throughout the day and night as prescribed. Cephalexin (Monohydrate) is important to take the drug for the full time period as prescribed. If you discontinue the therapy, it may result in ineffective treatment.


Brands
EUROCEF EUROCEF EUROCEF ANGLOLEXIN ANGLOLEXIN ANGLOLEXIN KEFLEX KEFLEX KEFLEX KEFLEX KEFLEX BENDROX BENDROX BENDROX CELERIM CELERIM CELERIM CELERIM KAVELEX KAVELEX KAVELEX KAVELEX KAVELEX CAMOCEP CAMOCEP CAMOCEP CAMOCEP CIBLEXIN CIBLEXIN CIBLEXIN ELEXIN ELEXIN ELEXIN ELEXIN CEFLIN CEFLIN CEFLIN CEFLIN CEFLIN CEPAXIN CEPAXIN CEPAXIN CEPAXIN CEFADROX CEFADROX CEFADROX CEFLEX SUSPENSION CEPOREX CEPOREX CEPOREX CEPOREX CEPOREX CEPOREX CEPOREX PAED CEFOCURE CEFOCURE CEFOCURE CEFOCURE KEFPORIN CEFLEX CEFLEX CEFLEX CEFLEX ULTROXIL CEPALEX CEPALEX MACLEXIN MACLEXIN MACLEXIN MACLEXIN MACLEXIN MACLEXIN MACLEXIN MACLEXIN NEULEXIN NEULEXIN OSPEXIN OSPEXIN OSPEXIN OSPEXIN OSPEXIN MURBEX MURBEX MURBEX MURBEX NENFLEX NENFLEX NENFLEX NENFLEX ORALEXIN ORALEXIN ORALEXIN ORALEXIN ORALEXIN ROXICEF ROXICEF ROXICEF MONOLEXIN MONOLEXIN CEFANEX CEFANEX CEFANEX CEFANEX REKOSPORIN REKOSPORIN REKOSPORIN REKOSPORIN SOLVOCEF SEFOLEX SEFOLEX SEFOLEX SEFOLEX SEFOLEX PLIVACEF PLIVACEF PLIVACEF PLIVACEF PALAXIN CEPHALEX CEPHALEX CEPHALEX CEPHALEX AG-CIN AG-CIN AG-CIN AG-CIN AG-CIN CEFALEX CEFALEX CEFALEX CEFALEX CEROX CEROX CEROX CEROX SAFEXIN SAFEXIN SAFEXIN SAFEXIN SPURGE SPURGE SPURGE SPURGE ZAFALEXIN ZAFALEXIN ZAFALEXIN ZAFALEXIN ZAFALEXIN ERADICIN ERADICIN EFALEXIN EFALEXIN EFALEXIN EFALEXIN KEPHALEXIN KEPHALEXIN KEPHALEXIN KEPHALEXIN BLOCEF BLOCEF BLOCEF BLOCEF KEFORAL KEFORAL KEFORAL KEFORAL KEFORAL KINGCEF KINGCEF D-MAX D-MAX D-MAX ORACEF ORACEF ORACEF ORACEF SAFALEX SAFALEX LEXHAL CEOXIL CEOXIL CEOXIL OCEFLOX OCEFLOX OCEFLOX OCEFLOX CEKALEXIN SPIC-LEXIN ZEPORIN ZEPORIN ZEPORIN ZEPORIN ZEPORIN LEXIWAN LEXIWAN LEXIWAN LEXIWAN ENVERA ENVERA JAFLEX JAFLEX JAFLEX JAFLEX IPRALEXIN IPRALEXIN IPRALEXIN IPRALEXIN RELIC RELIC DELEXIN DELEXIN DELEXIN DELEXIN ZAPHALEX ZAPHALEX ZAPHALEX ZAPHALEX CEPHALIN CEPHALIN CEPHALIN CEPHALIN LEADOXIN LEADOXIN LEADOXIN LEADOXIN B-LEX B-LEX B-LEX SYNAXIN SYNAXIN SYNAXIN SYNAXIN BACTEX BACTEX BACTEX BACTEX VG-LEX VG-LEX VG-LEX VG-LEX VG-LEX CEPEL-X DEFALEX DEFALEX DEFALEX DEFALEX LEXCEF LEXCEF LEXCEF LEXCEF LEXCEF ALEXIN ALEXIN ALEXIN ALEXIN NUFEX NUFEX NUFEX NUFEX WEBOLAXACIN WEBOLAXACIN WEBOLAXACIN WEBOLAXACIN FRELEXIN FRELEXIN FRELEXIN FRELEXIN LEXICEF LEXICEF LEXICEF LEXICEF CELEXIN CELEXIN CELEXIN CELEXIN CEFARID CEFARID PHAXIN PHAXIN ABIREX ABIREX ABIREX ABIREX MEDILEX MEDILEX MEDILEX MEDILEX CEPHCARE CEPHCARE CEPHCARE CEPHCARE CARAPHALEX CARAPHALEX CARAPHALEX CARAPHALEX JLEX JLEX JLEX JLEX KELEY KELEY KELEY KELEY CESAL CESAL CESAL C-XIN C-XIN C-XIN CEPOADVAN CEPOADVAN CEPOADVAN CEPOADVAN FASCEPH FASCEPH FASCEPH FASCEPH ASTELEXIN ASTELEXIN NAVELEX BAXCEPH WEFLEX Bacticlor Lexin Lexin Lexin Lexin
Adult Dose
Dose: 4 to 8 g
Single Dose: 6 (6)
Frequency: 8 hourly
Route: IV
Instructions: For sever infections. Frequency may be increased to 4 times/day if needed.
Neonatal
Dose: 7.812 mg/kg
Single Dose: 7.8 (7.812)
Frequency: 8 hourly
Route: oral
Instructions:
Paedriatic
Dose: 25 to 100 mg/kg
Single Dose: 62 (62.5)
Frequency: 12 hourly
Route: Oral
Instructions: For 5-12 Yrs of Children. To maximum of 4g individed doses.
Characteristics
Cephalexin (Monohydrate) also known as Cephalexin, Cephalexin. . It is of Semi Synthetic origin and belongs to Cephalosporin. It belongs to Peptidoglycan synthesis inhibitor pharmacological group on the basis of mechanism of action and also classified in Antibiotic, Cephalosporin pharmacological group.The Molecular Weight of Cephalexin (Monohydrate) is 365.40. Its pKa is 5.3-7.3.
Contraindications
Cephalexin (Monohydrate) is contraindicated in conditions like Hypersensitivity.
Effects
The severe or irreversible adverse effects of Cephalexin (Monohydrate), which give rise to further complications include Hypersensitivity reactions, Angioedema, Interstitial nephritis, Angioedema, Vulvo vaginitis.Cephalexin (Monohydrate) produces potentially life-threatening effects which include Pseudomembranous colitis. which are responsible for the discontinuation of Cephalexin (Monohydrate) therapy.The symptomatic adverse reactions produced by Cephalexin (Monohydrate) are more or less tolerable and if they become severe, they can be treated symptomatically, these include Dizziness, Headache, Nausea, Vomiting, Diarrhea, Skin reactions, Vaginitis, Genital moniliasis, Vaginal discharge, Neutropenia, GI disturbance, Genital pruritus, Anal pruritus, dizziness.
Indications
Cephalexin (Monohydrate) is primarily indicated in conditions like Bone and joint infection, Dental infections, Genitourinary tract infections, Otitis media, Respiratory tract infections, Schizophrenia and other psychoses, Skin infections, Soft tissue infections.
Interactions
No data regarding the interactions of Cephalexin (Monohydrate) was found.
Interfrence
False -ve urine glucose determinations
Risks
Drug should not be given to Pregnant Mothers, and Neonates.If prescribing authority justifies the benefits of the drug against the possible damages he/she should reevaluate them and consult the reference material and previous studies.
Storage
Oral Susp (reconstituted) Store in refrigerator. Use within 14 days if kept at room temperature. Tab, Caps, Dry Powder for Oral Susp Store Below 40°C. Protect from Sunlight and Moisture.
Warnings
Cephalexin should be used with caution in patients with impaired kidney or liver function, hypersensitive to penicillin. Appropriate measures should be taken if secondary infection occurs. It should be used with caution (if contains tartrazine) in patients with aspirin hypersensitivity, because it may cause allergic reactions (including bronchial asthma). Reduce dosage when renal function is markedly impaired.It should be used with caution during the first trimester of pregnancy.
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