Dronabinol

Dronabinol is a synthetic oral preparation of tetrahydrocannibinol (delta-9-THC), one of 66 cannabinoids found in Cannabis sativa. The synthetic form shares all the characteristics of the naturally occurring compound and is capable of producing physical and psychological dependence. Dronabinol is an antiemetic and used for the relief of nausea and vomiting secondary to cancer chemotherapy in patients who have failed to respond to other antiemetics. It also is used as an appetite stimulant in the treatment of anorexiaassociated with weight loss in patients with cancer and AIDS. It was approved by the FDA in May 1985.

Brands
Adult Dose
Dose: 2.5 mg
Single Dose: 2.5 (2.5)
Frequency: 12 hourly
Route: PO
Instructions: For Anorexia: This is initial dose. Should be taken before lunch and supper.
Neonatal
Paedriatic
Characteristics
Dronabinol also known as Tetra hydrocannobinol. . It is of Synthetic origin and belongs to Tetrahydrocannibinol. . The Molecular Weight of Dronabinol is 314.50.
Contraindications
Dronabinol is contraindicated in conditions like Hypersensitivity to the drug.
Effects
The symptomatic adverse reactions produced by Dronabinol are more or less tolerable and if they become severe, they can be treated symptomatically, these include Dizziness, Headache, Drowsiness, Irritability, Ataxia, Nausea, Vomiting, Diarrhea, Anxiety, Confusion, Hallucination, Dysphoria, Euphoria, Abdominal colic, Orthostatic hypotension, Xerostomia, Confusion, dizziness, Ataxia.
Indications
Dronabinol is primarily indicated in conditions like Anorexia, Nausea and vomiting.
Interactions
No data regarding the interactions of Dronabinol was found.
Interfrence
Risks
Drug should not be given to Paediatrics, and Cardiac / Hypertensive Patients.If prescribing authority justifies the benefits of the drug against the possible damages he/she should reevaluate them and consult the reference material and previous studies.
Storage
Caps Store in a well closed container, Below 15°C. Refrigeration and Freezing is not recommended. Protect from Sunlight.
Warnings
It should be used with caution in patients with cardiac disease because it can precipitate cardiacarrhythmias or angina, in patients with hypertension use with caution in pateint with sizures disorder. Patients with preexisting hypertension orhypotension can experience worsening of their condition if given dronabinol before their bloodpressure is corrected. Patients who are known to be substance abusers or have a history of substance abuse should be given with caution because of the potential for developing physical dependence. Elderly patients are generally more sensitive to the psychoactive effects of drugs and should be treated with caution. Because of its psychoactive potential, dronabinol is not recommended for use in children. It should be used with caution in the treatment of chmotherapy-induced emedidi in children. It is classified as pregnancy category B. Use with caution during pregnancy or lactation only if clearly needed. Pateints are worked not to drive, operate machinery or make judgement decisions.
Back to List

Any information that appears on this website page is provided for the purpose of general information. This website has been compiled in good faith by HMIS.Online. However, no guarantee is made as to the completeness, validity or accuracy of the information it contains.