Ropivacaine (HCl Monohydrate)

Ropivacaine (HCl Monohydrate) is a long-acting amide type local anaesthetic agent. It blocks pain by causing numbness or loss of feeling in an area of the body. Given before, during, or after surgery or childbirth, or at other times when pain needs to be controlled. Ropivacaine (HCl Monohydrate) is used for epidural block, peripheral nerve block and field blocks. At higher doses it produces surgical anaesthesia, whereas at lower doses Ropivacaine (HCl Monohydrate) is used for the management of acute pain such as labour pain and postoperative pain. Like Bupivacaine, ropivacaine has a differential blocking effect on nerve fibres and, at the lowest concentration used, there is good differentiation between sensory and motor block.

Brands
ROPICAIN
Adult Dose
Neonatal
Paedriatic
Characteristics
. It is of Synthetic origin and belongs to Amide. . The Molecular Weight of Ropivacaine (HCl Monohydrate) is 328.90. Its pKa is 8.1.
Contraindications
Ropivacaine (HCl Monohydrate) is contraindicated in conditions like Hypersensitivity.
Effects
Ropivacaine (HCl Monohydrate) produces potentially life-threatening effects which include Convulsions, Cardiac depression. which are responsible for the discontinuation of Ropivacaine (HCl Monohydrate) therapy.The signs and symptoms that are produced after the acute overdosage of Ropivacaine (HCl Monohydrate) include Dizziness, Paresthesia, Visual distrubances, Loss of conciousness.The symptomatic adverse reactions produced by Ropivacaine (HCl Monohydrate) are more or less tolerable and if they become severe, they can be treated symptomatically, these include Dizziness, Headache, Pruritus, Bradycardia, Hypotension, Nausea and vomiting.
Indications
Ropivacaine (HCl Monohydrate) is primarily indicated in conditions like Acute pain, Epidural analgesia in labor, Field block, Peripheral nerve block, Post operative analgesia, Post-operative epidural infusion, Surgical anaesthesia, Wound infiltration.
Interactions
No data regarding the interactions of Ropivacaine (HCl Monohydrate) was found.
Interfrence
Risks
Drug should not be given to Paediatrics, Pregnant Mothers, Cardiac / Hypertensive Patients, and patients suffering from Liver Malfunction.If prescribing authority justifies the benefits of the drug against the possible damages he/she should reevaluate them and consult the reference material and previous studies.
Storage
Inj, Inf Store at room temperature. Do not Freeze.
Warnings
Avoid in patient with known hypersensitivity. It should be given with caution to the elderly, to debilitated, to children, patients with epilepsy, impaired cardiac conduction or respiratory function, shock or liver damage. The application of local anesthatics to the skin for prolonged period or to the extensive area should be avoided.
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