Dopexamine (HCl)

Dopexamine (HCl) is a sympathomimetic, stimulates beta-2 adrenoceptorsand peripheral dopamine receptors. It also inhibits neuronal reuptake of noradrenaline. Dopexamine (HCl) is used to provide haemodynamic support that may be required after cardiac surgery or in exacerbation of chronic heart failure.dipexamine (Dopacard) is a synthetic analog related to dopermine with intsinic activity at dopamine D1 and D2 receptors as well as at b2 receptors; it may have others effects such as inhibition of catecholamine up take in patients with law cardiac output, dopexamine infusion significantly increase stroke volume with a decrease in systemic mascular resistance.

Brands
Adult Dose
Neonatal
Paedriatic
Characteristics
. It is of Synthetic origin. . The Molecular Weight of Dopexamine (HCl) is 429.40.
Contraindications
Dopexamine (HCl) is contraindicated in conditions like Hypovolaemia,Myocardial infarction,Phaeochromocytoma,Thyrotoxicosis,Thrombocytopenia,Left ventricular outflow obstruction.
Effects
The signs and symptoms that are produced after the acute overdosage of Dopexamine (HCl) include Hypotension, Nausea, Vomiting, Tachycardia, Ventricular arrhythmias, Tremulousness, Ischemic chest pain.The symptomatic adverse reactions produced by Dopexamine (HCl) are more or less tolerable and if they become severe, they can be treated symptomatically, these include Headache, Nausea, Vomiting, Dyspnea, Tachycardia, Sweating, Hypotension, Tremor, Thrombocytopenia, Chest pain, Angina, Atrial fibrillation, Supraventricular tachycardia, Decreased sweating, Cardiac failure, Arrhythmia.
Indications
Dopexamine (HCl) is primarily indicated in conditions like Cardiac surgery, Chronic heart failure, Heart failure associated with cardiac surgery, Inotropic support and vaso, Sedation of patients receiving intensive care, and can also be given in adjunctive therapy as an alternative drug of choice in Acute exacerbation of chronic heart failure, Sepsis, Shock.
Interactions
No data regarding the interactions of Dopexamine (HCl) was found.
Interfrence
Risks
If prescribing authority justifies the benefits of the drug against the possible damages he/she should reevaluate them and consult the reference material and previous studies.
Storage
IV Inf Store Below 25°C. Protect from Sunlight.
Warnings
It should be used with caution in patients with ischemic heart disease or following mayocardial infarction. Care is required in presence of hyperglycemia or hypokalemia. Pre-existing hypotension and reduced vascular resistance should be corrected before begining dopexamine administration.Cuation:- Mycordial infraction , recent angina, hypokalcemia,hyperglycemia;correct hyponolaemia before starting and during treatment monitor blood pressure, pulse,plasma potassium and blood glucose; hyperthysoidism; aviod absupt with drawal.
Back to List

Any information that appears on this website page is provided for the purpose of general information. This website has been compiled in good faith by HMIS.Online. However, no guarantee is made as to the completeness, validity or accuracy of the information it contains.