Cefprozil (Monohydrate)

Cefprozil (Monohydrate) is an oral second generation cephalosporin antibiotic. Cefprozil (Monohydrate) is useful for urinary tract infections which donot respond to other drug.


Adult Dose
Neonatal
Paedriatic
Dose: 20 mg/kg
Single Dose: 20 (20)
Frequency: 24 hourly
Route: to maximum of 500 mg once a twice daily
Instructions:
Characteristics
. It is of Semi Synthetic origin and belongs to Cephalosporin. . The Molecular Weight of Cefprozil (Monohydrate) is 407.50. Its pKa is 2.8, 7.3, 9.7.
Contraindications
Cefprozil (Monohydrate) is contraindicated in conditions like Hypersensitivity.
Effects
The severe or irreversible adverse effects of Cefprozil (Monohydrate), which give rise to further complications include Serum sickness.Cefprozil (Monohydrate) produces potentially life-threatening effects which include Pseudomembranous colitis. which are responsible for the discontinuation of Cefprozil (Monohydrate) therapy.The symptomatic adverse reactions produced by Cefprozil (Monohydrate) are more or less tolerable and if they become severe, they can be treated symptomatically, these include Dizziness, Headache, Nausea, Vomiting, Diarrhea, Insomnia, Nervousness, Abdominal pain, Skin rashes, Vaginitis, Genital pruritus.
Indications
Cefprozil (Monohydrate) is primarily indicated in conditions like Acute exacerbation of chronic bronchitis, Chronic bronchitis, Epidural block, surgery, Lower respiratory tract infections, Otitis media, Pharyngitis, Pneumonia, Skin and soft tissue infections, Skin infections, Tonsillitis, Upper respiratory tract infections, Upper UTIs.
Interactions
No data regarding the interactions of Cefprozil (Monohydrate) was found.
Interfrence
False +ve Coombs Test False +ve Urinary Glucose Test (Clinitest)
Risks
Drug should not be given to Pregnant Mothers, and Neonates.If prescribing authority justifies the benefits of the drug against the possible damages he/she should reevaluate them and consult the reference material and previous studies.
Storage
Tab, Powder Store in a well closed container, at room temperature, Between 15°C-25°C.
Warnings
It should be used with care in patients with impaired kidney or liver function. Appropriate measure should be taken if secondary infection occurs. It should be used with caution (if contain tartrazine) in patients with aspirin hypersensitivity, because it may cause allergic reactions (including bronchial asthma).
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