Cefodizime (Na)

Cefodizime (Na) is a third generation cephalosporin antibiotic with actions, uses and adverse effects similar to those of cefotaxime. Cefodizime (Na) is given parentrally in the treatment of susceptible infections.


Brands
Adult Dose
Neonatal
Paedriatic
Characteristics
. It is of Semi Synthetic origin and belongs to Aminothiazolyl cephalosporin. . The Molecular Weight of Cefodizime (Na) is 628.60. Its pKa is 2.85, 3.37, 4.18.
Contraindications
Cefodizime (Na) is contraindicated in conditions like Impaired renal function,Hypersensitivity.
Effects
The severe or irreversible adverse effects of Cefodizime (Na), which give rise to further complications include Allergy, Thrombocytopenia, Hemolytic anemia, Eosinophilia, Angioedema, Leucopenia, Anaphylaxis.Cefodizime (Na) produces potentially life-threatening effects which include Anaphylactic shock. which are responsible for the discontinuation of Cefodizime (Na) therapy.The signs and symptoms that are produced after the acute overdosage of Cefodizime (Na) include Encephalopathy.The symptomatic adverse reactions produced by Cefodizime (Na) are more or less tolerable and if they become severe, they can be treated symptomatically, these include Dizziness, Vertigo, Headache, Nausea, Vomiting, Diarrhea, Skin RashX, Cutaneous eruption.
Indications
Cefodizime (Na) is primarily indicated in conditions like Pelvic infections, Respiratory tract infections, Urinary tract infection.
Interactions
No data regarding the interactions of Cefodizime (Na) was found.
Interfrence
Jaffe method for determining Creatinine
Risks
Drug should not be given to Paediatrics, Pregnant Mothers, patients suffering from Kidney dysfunction, Geriatrics, and Neonates.If prescribing authority justifies the benefits of the drug against the possible damages he/she should reevaluate them and consult the reference material and previous studies.
Storage
Inj (reconstituted soln) Store in refrigerator. Use within 24 hrs if kept at room temperature. Powder for Inj Store Below 25°C. Protect from Sunlight and Moisture.
Warnings
It should be used with caution in patients with impaired kidney or liver function. Appropriate measure should be taken if secondary infection occurs. It should be used with caution (if contain tartrazine) in patients with aspirin hypersensitivity, because it may cause allergic reactions (including bronchial asthma).
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